{"id":"W2127583354","doi":"10.1186/2045-7022-2-7","title":"Repeated allergen exposure reduce early phase airway response and leukotriene release despite upregulation of 5‐lipoxygenase pathways","year":2012,"lang":"en","type":"article","venue":"Clinical and Translational Allergy","topic":"Mast cells and histamine","field":"Immunology and Microbiology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Gilead Sciences (Canada)","funders":"Lunds Universitet; Vårdalstiftelsen","keywords":"Allergen; Leukotriene; Medicine; Immunology; Histamine; Leukotriene C4; Bronchoconstriction; Cyclooxygenase; Thromboxane A2; Allergy; Pharmacology; Asthma; Chemistry; Enzyme; Biochemistry; Platelet","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007600723,0.0001701944,0.0003270035,0.0000724527,0.0001420051,0.000007268527,0.00007020173,0.0002945698,0.0005158152],"category_scores_gemma":[0.000117371,0.0001488381,0.0001099994,0.00009409256,0.0004192824,0.0001465846,0.00002729295,0.0001950139,0.00002108022],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000003415454,"about_ca_system_score_gemma":0.00005487442,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000298684,"about_ca_topic_score_gemma":0.00001238964,"domain_scores_codex":[0.9982781,0.0003800826,0.0007239138,0.0003053092,0.00006306502,0.0002495348],"domain_scores_gemma":[0.9989465,0.0004844584,0.0001679091,0.0001837954,0.00009969773,0.0001176298],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.03933401,0.003977314,0.05244967,0.0001173209,0.001184789,0.00001937832,0.004033818,0.00007357047,0.7274089,0.01583993,0.001364489,0.1541968],"study_design_scores_gemma":[0.01113233,0.001435914,0.8803811,0.00005336953,0.00008706624,0.00004010743,0.00006254989,0.0001225849,0.01362737,0.0006600049,0.09203248,0.0003651399],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9910163,0.007403217,0.0003666093,0.0004141517,0.0002541189,0.0001634038,0.0001000331,0.00003086089,0.0002512591],"genre_scores_gemma":[0.9975016,0.0005051129,0.0003102667,0.00006259306,0.00009040719,0.000009375857,0.0002299295,0.00001521446,0.001275519],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8279314,"threshold_uncertainty_score":0.6069441,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03628026063103715,"score_gpt":0.2883424513865272,"score_spread":0.25206219075549,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}