{"id":"W2127599923","doi":"10.1074/jbc.275.30.23020","title":"Substrate Specificity in Glycoside Hydrolase Family 10","year":2000,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Enzyme Production and Characterization","field":"Biochemistry, Genetics and Molecular Biology","cited_by":80,"is_retracted":false,"has_abstract":true,"ca_institutions":"Armand Frappier Museum; Institut National de la Recherche Scientifique","funders":"","keywords":"Glycoside hydrolase; Substrate (aquarium); Hydrolase; Substrate specificity; Glycoside; Chemistry; Stereochemistry; Biochemistry; Biology; Enzyme; Ecology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002013464,0.0001071997,0.0001520339,0.00001462918,0.00002262148,0.00001494687,0.0001495076,0.0001902371,0.001131867],"category_scores_gemma":[0.00007112977,0.00008319161,0.00009363985,0.00008021896,0.00005872407,0.00000551356,0.00001687177,0.0001738701,0.00001803725],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000161828,"about_ca_system_score_gemma":0.00003361321,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":9.875932e-7,"about_ca_topic_score_gemma":4.578342e-7,"domain_scores_codex":[0.9991993,0.00003686823,0.0003587306,0.000173221,0.00008812327,0.0001438042],"domain_scores_gemma":[0.9995815,0.000006444303,0.0001404743,0.0001254551,0.00006658381,0.000079586],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003678154,0.0001135665,0.003191142,0.000006005006,0.00000946703,0.0000197686,0.000005657496,0.0000597644,0.9941961,7.673225e-7,0.0006300514,0.001399865],"study_design_scores_gemma":[0.000464805,0.0001445007,0.02072742,0.00001186907,0.00000370533,0.0001207961,0.00003117812,0.000009252173,0.9386801,0.00004471092,0.03964742,0.0001142596],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9957757,0.000381481,0.00002622078,0.0001669192,0.00004904296,0.00002871627,0.000005554781,0.000004562017,0.003561804],"genre_scores_gemma":[0.9968697,0.0008473782,0.0001158385,0.0001596688,0.0005252558,0.000001238406,0.00004059107,0.00000589313,0.00143441],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05551605,"threshold_uncertainty_score":0.9997813,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01816449133434381,"score_gpt":0.237629803772906,"score_spread":0.2194653124385622,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}