{"id":"W2127604250","doi":"10.1128/iai.68.11.6402-6410.2000","title":"Identification of<i>tgh-2</i>, a Filarial Nematode Homolog of<i>Caenorhabditis elegans daf-7</i>and Human Transforming Growth Factor β, Expressed in Microfilarial and Adult Stages of<i>Brugia malayi</i>","year":2000,"lang":"en","type":"article","venue":"Infection and Immunity","topic":"GDF15 and Related Biomarkers","field":"Medicine","cited_by":163,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Medical Research Council; Leverhulme Trust; York University","keywords":"Biology; Brugia malayi; Caenorhabditis elegans; Peptide sequence; Cell biology; Schneider 2 cells; Gene; Molecular biology; Genetics; RNA interference; Immunology; RNA; Helminths","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002592785,0.0001481987,0.0003863465,0.0002060494,0.0001060752,0.00001452299,0.00004057389,0.0002318768,0.00006643414],"category_scores_gemma":[0.00006092362,0.0001345134,0.00006985822,0.0002063359,0.0002732843,0.0001828394,0.00001793181,0.0002718926,4.563061e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001450133,"about_ca_system_score_gemma":0.00003276888,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004085531,"about_ca_topic_score_gemma":0.0001070154,"domain_scores_codex":[0.9988506,0.0001388237,0.0005718215,0.0001762485,0.0001205709,0.0001419348],"domain_scores_gemma":[0.9994233,0.00006744762,0.0001768092,0.0001582184,0.0001127183,0.0000615282],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0004792201,0.0002324449,0.1325772,0.0004914373,0.00009373479,0.000003192298,0.00135929,9.380404e-7,0.8619214,0.0001631024,0.00002407329,0.00265396],"study_design_scores_gemma":[0.003800378,0.0003791878,0.5999762,0.0002299231,0.000124945,0.00006585904,0.0001838497,0.00001931337,0.3948643,0.0001106565,0.0001210048,0.0001244035],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9985803,0.0002386417,0.00006757598,0.00007387196,0.00009588228,0.0003682335,0.00007589268,0.00002076484,0.0004788453],"genre_scores_gemma":[0.9980941,0.001693954,0.00004077676,0.00001817879,0.0000244317,0.000007866011,0.00004291421,0.00001247575,0.00006524014],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.467399,"threshold_uncertainty_score":0.6176128,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006530472058908767,"score_gpt":0.2412720666717351,"score_spread":0.2347415946128263,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}