{"id":"W2127604521","doi":"10.1093/ntr/ntv125","title":"The Nicotine Metabolite Ratio is Associated With Early Smoking Abstinence Even After Controlling for Factors That Influence the Nicotine Metabolite Ratio","year":2015,"lang":"en","type":"article","venue":"Nicotine & Tobacco Research","topic":"Smoking Behavior and Cessation","field":"Medicine","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"National Institute on Drug Abuse; Centre for Addiction and Mental Health Foundation; Ontario Ministry of Research and Innovation; Campbell Family Mental Health Research Institute; National Institutes of Health; Canadian Institutes of Health Research","keywords":"CYP2A6; Cotinine; Nicotine; Metabolite; Abstinence; Smoking cessation; Nicotine dependence; Medicine; Pharmacology; Chemistry; Internal medicine; Psychiatry; Metabolism","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003574413,0.0003875029,0.0006529422,0.0003922779,0.0003007803,0.0006453054,0.0004379512,0.000566536,0.003722978],"category_scores_gemma":[0.00572843,0.0003009215,0.001153082,0.0005198932,0.0003098338,0.0003990699,0.0004095907,0.001023518,0.0003217309],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001546572,"about_ca_system_score_gemma":0.0003681668,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001654423,"about_ca_topic_score_gemma":0.00204225,"domain_scores_codex":[0.9979928,0.0008297429,0.0001206466,0.000566853,0.0003400021,0.0001500285],"domain_scores_gemma":[0.9928603,0.003677821,0.002217686,0.0005065286,0.0002915992,0.0004460405],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.002776575,0.0001134774,0.9824702,0.00007754993,0.001330243,0.00007154427,0.00005955965,0.0001139445,0.002195356,0.00006706038,0.0001721594,0.01055216],"study_design_scores_gemma":[0.00002453081,0.0003590708,0.9980499,0.00001363043,0.0005202143,0.0001335668,0.00001872728,0.0003758412,0.0001970876,0.00005975425,0.0002446387,0.000003141034],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.993068,0.002739712,0.001512493,0.0002723892,0.00004256988,0.00003421878,0.0005649105,0.00005166744,0.001714095],"genre_scores_gemma":[0.9983884,0.0002671935,0.0004466495,0.00005702006,0.00002909013,0.00001707679,0.0002039017,0.00001220347,0.000578577],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003722978,"threshold_uncertainty_score":0.01890355,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09711775666567334,"score_gpt":0.3656879448765843,"score_spread":0.268570188210911,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}