{"id":"W2127647346","doi":"10.1074/jbc.m301006200","title":"Overexpression of the 78-kDa Glucose-regulated Protein/Immunoglobulin-binding Protein (GRP78/BiP) Inhibits Tissue Factor Procoagulant Activity","year":2003,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Endoplasmic Reticulum Stress and Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":57,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ontario Institute for Cancer Research; McMaster University; McMaster University Medical Centre","funders":"Heart and Stroke Foundation of Canada","keywords":"Tissue factor; Glucose-regulated protein; Thrombin; Thrombomodulin; Molecular biology; Factor VII; Cell culture; Endoplasmic reticulum; Transfection; Chemistry; Thromboplastin; Unfolded protein response; Tissue factor pathway inhibitor; Cell; Cell biology; Biology; Coagulation; Biochemistry; Immunology; Internal medicine; Medicine; Platelet","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000159969,0.0004391435,0.0004621608,0.0001917053,0.0001535335,0.0003255007,0.0003090963,0.0002896932,0.0008524603],"category_scores_gemma":[0.0001566313,0.0001382925,0.000289205,0.0002846968,0.0002391071,0.0001977501,0.0001762974,0.0005016888,0.0005699606],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002868461,"about_ca_system_score_gemma":0.0001626289,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007866836,"about_ca_topic_score_gemma":0.00057461,"domain_scores_codex":[0.9997616,0.0000405766,0.00002733811,0.00003294462,0.00006044068,0.00007709094],"domain_scores_gemma":[0.9998388,0.00002578182,0.00004970155,0.00002353943,0.00001832789,0.00004373707],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008551888,0.00003527994,0.00004988948,0.00002599207,0.000005067336,0.00003108219,0.000006225397,0.00004412008,0.9991053,0.00003016217,0.00003916475,0.0005421796],"study_design_scores_gemma":[0.00003048756,0.0006640852,0.003522375,0.000005413519,0.00002862828,0.000375347,0.00002520832,0.001757777,0.9904487,0.00002964781,0.003105895,0.000006490767],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9937402,0.001628292,0.002875607,0.0001579498,0.00005375851,0.0000279809,0.0004786603,0.0001820687,0.0008554304],"genre_scores_gemma":[0.9917052,0.001163897,0.003976236,0.00007402225,0.00001423032,0.00004462328,0.001296968,0.00006055295,0.00166432],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008524603,"threshold_uncertainty_score":0.002851784,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01410321495519433,"score_gpt":0.247338315835714,"score_spread":0.2332351008805197,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}