{"id":"W2127652579","doi":"10.1091/mbc.12.11.3386","title":"In Vivo Association of Ku with Mammalian Origins of DNA Replication","year":2001,"lang":"en","type":"article","venue":"Molecular Biology of the Cell","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":62,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; McGill University Health Centre","funders":"Canadian Institutes of Health Research","keywords":"Ku80; Biology; Ku70; DNA replication; Origin recognition complex; Replication factor C; S phase; Molecular biology; DNA polymerase delta; Control of chromosome duplication; DNA; Eukaryotic DNA replication; Replication protein A; Cell cycle; DNA repair; DNA synthesis; Cell biology; DNA-binding protein; Genetics; Polymerase chain reaction; Cell; Gene; Reverse transcriptase; Transcription factor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002828247,0.00008850099,0.0001626923,0.00004169736,0.00001092617,9.422229e-7,0.0002119941,0.0001807474,0.00001464396],"category_scores_gemma":[0.00006767581,0.00006772773,0.0000823327,0.0001442186,0.00007261566,0.000001747384,0.00007316206,0.00005082804,6.595729e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003624982,"about_ca_system_score_gemma":0.00004579965,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007710404,"about_ca_topic_score_gemma":0.00004968202,"domain_scores_codex":[0.9991933,0.0001272706,0.0002359119,0.0002269908,0.00008422877,0.0001323702],"domain_scores_gemma":[0.9989199,0.00000918974,0.0003589204,0.0006016721,0.00009311821,0.00001718845],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006902118,0.00008094811,0.0160289,0.00001754571,0.00002622092,0.000001021466,0.0000194246,0.00004121359,0.9828888,0.0006873955,0.00008071178,0.0000587567],"study_design_scores_gemma":[0.0005295818,0.0002901728,0.001092031,0.0000102157,0.00002061141,0.000004699177,0.0000143037,0.00001567654,0.992726,0.0004095421,0.004819389,0.0000677947],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969828,0.0001076844,0.00117605,0.0002265813,0.00005651063,0.000180473,0.00001528469,0.000002749679,0.001251874],"genre_scores_gemma":[0.998001,0.00003230242,0.001008269,0.00008719614,0.00001242226,0.000008924452,0.00001670246,0.00001111737,0.0008220575],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01493687,"threshold_uncertainty_score":0.2761857,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004279371249134717,"score_gpt":0.2267524828101854,"score_spread":0.2224731115610507,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}