{"id":"W2127720026","doi":"10.1095/biolreprod.113.115899","title":"Adult Glucocorticoid Exposure Leads to Transcriptional and DNA Methylation Changes in Nuclear Steroid Receptors in the Hippocampus and Kidney of Mouse Male Offspring1","year":2014,"lang":"en","type":"article","venue":"Biology of Reproduction","topic":"Birth, Development, and Health","field":"Medicine","cited_by":69,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; McGill University","funders":"Canadian Institutes of Health Research","keywords":"Offspring; DNA methylation; Biology; Endocrinology; Internal medicine; Glucocorticoid receptor; Methylation; Nuclear receptor; Estrogen receptor; Glucocorticoid; Estrogen receptor alpha; Mineralocorticoid receptor; Receptor; Kidney; Gene expression; Aldosterone; Pregnancy; Transcription factor; Cancer; Medicine; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001391293,0.0004818676,0.0004247986,0.0006671358,0.0001859181,0.000336518,0.0003360417,0.0003720157,0.001953369],"category_scores_gemma":[0.0001224266,0.0003303602,0.0004666443,0.0002270683,0.0003748251,0.0002234034,0.000311464,0.0008407724,0.0005158423],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003952243,"about_ca_system_score_gemma":0.0002927545,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00232088,"about_ca_topic_score_gemma":0.004592362,"domain_scores_codex":[0.9996917,0.00001568666,0.00002203045,0.0001152094,0.00008446578,0.00007083097],"domain_scores_gemma":[0.9997612,0.0000148613,0.00009695886,0.00002329884,0.00002723235,0.00007654198],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001359953,0.00001415017,0.0005646566,0.00002073895,0.000008947222,0.00006036223,0.0000268666,0.000009094207,0.9983888,0.00002876195,0.00003290792,0.0007087516],"study_design_scores_gemma":[0.00002162766,0.0007710456,0.06943908,0.00001853165,0.00006482915,0.0006195895,0.0001562547,0.0001835739,0.926291,0.00006788059,0.002350068,0.00001650362],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9882764,0.004158631,0.003307373,0.0001564267,0.00008245317,0.00003302283,0.002271856,0.0001989644,0.001514855],"genre_scores_gemma":[0.9813499,0.003026217,0.002784094,0.0001743637,0.00002511229,0.00008669272,0.002394379,0.00009515305,0.01006398],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00232088,"threshold_uncertainty_score":0.006534636,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01892521740674158,"score_gpt":0.2622566113644819,"score_spread":0.2433313939577403,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}