{"id":"W2127729727","doi":"10.1128/aac.47.7.2082-2087.2003","title":"<i>Burkholderia pseudomallei</i> Class A β-Lactamase Mutations That Confer Selective Resistance against Ceftazidime or Clavulanic Acid Inhibition","year":2003,"lang":"en","type":"article","venue":"Antimicrobial Agents and Chemotherapy","topic":"Burkholderia infections and melioidosis","field":"Medicine","cited_by":101,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Sciences Centre; University of Calgary","funders":"","keywords":"Burkholderia pseudomallei; Melioidosis; Ceftazidime; Microbiology; Clavulanic acid; Biology; Burkholderia; Antibiotics; Bacteria; Genetics; Amoxicillin","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006679381,0.0001866633,0.0001025301,0.0001256337,0.00008506991,0.0002389886,0.0000966237,0.0001446316,0.0009151136],"category_scores_gemma":[0.0002215959,0.00007532596,0.0001197898,0.00009533251,0.0001128982,0.0001409792,0.0001193642,0.0002100108,0.0003902968],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001569499,"about_ca_system_score_gemma":0.00008933145,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000553015,"about_ca_topic_score_gemma":0.0006949728,"domain_scores_codex":[0.9999402,0.00001052356,0.000005437665,0.00001234294,0.0000164897,0.000015007],"domain_scores_gemma":[0.9998724,0.00002303826,0.00005086351,0.00001462592,0.0000152876,0.00002374234],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005279813,0.00001689973,0.001615089,0.00001291359,0.00000218866,0.0001211008,0.00001044341,0.00003033524,0.9964915,0.00008488334,0.00002290095,0.001538969],"study_design_scores_gemma":[0.00001102167,0.0002199564,0.02431276,0.000006358115,0.00001050836,0.001957534,0.00004895452,0.0007270277,0.9696991,0.00009822893,0.002903899,0.000004679153],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9962851,0.0003196977,0.002191724,0.00005324008,0.00001139591,0.00001687833,0.0002204193,0.00005253062,0.0008489785],"genre_scores_gemma":[0.9964269,0.0001467474,0.002220812,0.00002534664,0.000004030789,0.000007460525,0.0004014215,0.000008732974,0.0007584996],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009151136,"threshold_uncertainty_score":0.003061354,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0223126923807761,"score_gpt":0.2613704381427949,"score_spread":0.2390577457620188,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}