{"id":"W2127763131","doi":"10.1097/01.tp.0000164512.99703.ad","title":"Pharmacodynamics of Oral Ganciclovir and Valganciclovir in Solid Organ Transplant Recipients","year":2005,"lang":"en","type":"article","venue":"Transplantation","topic":"Cytomegalovirus and herpesvirus research","field":"Medicine","cited_by":201,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto General Hospital; University of Toronto","funders":"","keywords":"Valganciclovir; Ganciclovir; Medicine; Pharmacokinetics; Neutropenia; Gastroenterology; Internal medicine; Viremia; Leukopenia; Pharmacodynamics; Toxicity; Human cytomegalovirus; Immunology; Virus","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000955127,0.0005288661,0.001222668,0.0001857873,0.0001759198,0.0004783625,0.0003078877,0.0006479337,0.001396666],"category_scores_gemma":[0.001607263,0.0002479366,0.0006049746,0.0001759676,0.0006332555,0.0004248451,0.0002003962,0.00101754,0.0002677645],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002903485,"about_ca_system_score_gemma":0.0003928929,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001240094,"about_ca_topic_score_gemma":0.0001267188,"domain_scores_codex":[0.9993699,0.0003247158,0.00004936098,0.00007584178,0.00007922458,0.0001010287],"domain_scores_gemma":[0.9989951,0.000333221,0.0002981248,0.00006440874,0.0000286156,0.0002806163],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.8421054,0.01539901,0.01382273,0.0004946808,0.0005819438,0.0001035849,0.00006727629,0.001186401,0.03238995,0.00009007337,0.0003820066,0.09337694],"study_design_scores_gemma":[0.1850248,0.7604006,0.03668272,0.00004291455,0.0006006799,0.000374307,0.00004969788,0.002097338,0.01335852,0.0001859668,0.001154822,0.0000276893],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9983659,0.0008366372,0.000263492,0.00004678639,0.00002969786,0.0001474271,0.0000566635,0.0000208257,0.0002324828],"genre_scores_gemma":[0.9985867,0.000250242,0.0004239072,0.0001251212,0.00007714366,0.0002742558,0.0000935282,0.000004640899,0.0001645397],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001396666,"threshold_uncertainty_score":0.005051196,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02244610705658404,"score_gpt":0.3401491752693451,"score_spread":0.3177030682127611,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}