{"id":"W2127901736","doi":"10.1093/infdis/jit465","title":"Protection Against Lethal Marburg Virus Infection Mediated by Lipid Encapsulated Small Interfering RNA","year":2013,"lang":"en","type":"article","venue":"The Journal of Infectious Diseases","topic":"Viral Infections and Outbreaks Research","field":"Medicine","cited_by":55,"is_retracted":false,"has_abstract":true,"ca_institutions":"Arbutus Biopharma (Canada)","funders":"National Institute of Allergy and Infectious Diseases; Natural Sciences and Engineering Research Council of Canada; University of Texas Medical Branch","keywords":"Small interfering RNA; Marburg virus; In vivo; In vitro; Virology; RNA interference; Messenger RNA; Biology; Virus; RNA; Medicine; Biochemistry; Gene; Ebola virus; Biotechnology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001907995,0.0004965083,0.0002185734,0.0002032761,0.000117621,0.0002152788,0.00019826,0.000326409,0.001034717],"category_scores_gemma":[0.0001464151,0.0001008217,0.0002643215,0.00005385309,0.0001994863,0.000192178,0.0001437237,0.0004715711,0.0003191607],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001407227,"about_ca_system_score_gemma":0.0001692824,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002035822,"about_ca_topic_score_gemma":0.0002484513,"domain_scores_codex":[0.9999248,0.00001546682,0.000005630665,0.00001461495,0.0000202399,0.00001931618],"domain_scores_gemma":[0.9999191,0.00002690414,0.00002079451,0.000007916503,0.00001291058,0.00001252362],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000111922,0.00005103189,0.00008249418,0.00004873948,0.000004444427,0.00002026587,0.00001346425,0.00006783715,0.996927,0.00005583098,0.00003758989,0.002579402],"study_design_scores_gemma":[0.00002839408,0.001477854,0.0007639998,0.000007063572,0.00001751386,0.000108182,0.000008729595,0.0005136651,0.9958827,0.0000280446,0.001160858,0.000002926333],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9896901,0.002462293,0.005655771,0.0001157992,0.00004801595,0.00007186289,0.0001364372,0.0001512601,0.001668511],"genre_scores_gemma":[0.9915753,0.001662752,0.004625459,0.00005784154,0.00002092839,0.00006048039,0.0003333023,0.00001921695,0.001644752],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001034717,"threshold_uncertainty_score":0.003461421,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01802249567540662,"score_gpt":0.264795676074199,"score_spread":0.2467731803987924,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}