{"id":"W2127933655","doi":"10.1093/molehr/gam077","title":"Toward gene therapy of primary ovarian failure: adenovirus expressing human FSH receptor corrects the Finnish C566T mutation","year":2007,"lang":"en","type":"article","venue":"Molecular Human Reproduction","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Center for Research Resources","keywords":"Biology; Mutation; Genetic enhancement; Follicle-stimulating hormone receptor; Receptor; Gene; Gonadotropin; Genetics; Internal medicine; Endocrinology; Follicle-stimulating hormone; Hormone","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000332919,0.0003578115,0.0002749696,0.000267136,0.0001696212,0.0003902056,0.0002336688,0.0003224715,0.001498983],"category_scores_gemma":[0.0001432913,0.0001377115,0.000346989,0.0001868624,0.0002748254,0.000174211,0.0002143379,0.0005560942,0.0004771497],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002499502,"about_ca_system_score_gemma":0.0002781906,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008269587,"about_ca_topic_score_gemma":0.000617301,"domain_scores_codex":[0.9998302,0.00003379142,0.00001771175,0.0000340349,0.00004415192,0.00004002111],"domain_scores_gemma":[0.9999355,0.00001322844,0.00001541409,0.00001078755,0.00001143313,0.00001362509],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001693584,0.0001016762,0.0001899096,0.00009623427,0.000009167273,0.0001462273,0.00004604619,0.0001036819,0.9935048,0.0005794798,0.0001755376,0.004877967],"study_design_scores_gemma":[0.0001448349,0.0015314,0.001403205,0.00001967667,0.00006471007,0.001392507,0.00005355038,0.001285229,0.9760975,0.000111893,0.01788602,0.000009535436],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9565534,0.005151613,0.02943624,0.0005856163,0.0003953559,0.0004948787,0.0007924695,0.000329876,0.006260556],"genre_scores_gemma":[0.9669073,0.004550316,0.01999528,0.00009947138,0.00004284523,0.0001897971,0.0008980943,0.00004359954,0.007273298],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001498983,"threshold_uncertainty_score":0.005014658,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03064121930784948,"score_gpt":0.299273239295563,"score_spread":0.2686320199877136,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}