{"id":"W2127970706","doi":"10.1038/srep04549","title":"Stearoyl-CoA desaturase inhibition blocks formation of hepatitis C virus-induced specialized membranes","year":2014,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Hepatitis C virus research","field":"Medicine","cited_by":64,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa; Memorial University of Newfoundland; National Research Council Canada","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Hepatitis C virus; Replication (statistics); Viral replication; Host factor; Membrane; Chemistry; Membrane fluidity; Biosynthesis; Biochemistry; Fatty acid; Nuclease; Virus; Biology; Cell biology; Virology; Enzyme; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001645364,0.000348631,0.0004567827,0.0002161072,0.0001617093,0.0003078519,0.0002834236,0.0002956641,0.0009549819],"category_scores_gemma":[0.0001688487,0.0001366653,0.0002137746,0.0001252747,0.0003703866,0.000183344,0.0001900922,0.0007012145,0.0002763191],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003326166,"about_ca_system_score_gemma":0.0004139316,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007626042,"about_ca_topic_score_gemma":0.001675806,"domain_scores_codex":[0.9998168,0.00003567581,0.00002599392,0.00002856197,0.00003728176,0.00005562175],"domain_scores_gemma":[0.9998735,0.00003214536,0.00003481131,0.00001442065,0.00001246055,0.00003258336],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00059621,0.0001302548,0.0001703254,0.00003295733,0.00001126666,0.00002706571,0.00001153562,0.0001322894,0.9962009,0.0001188218,0.00006395706,0.002504424],"study_design_scores_gemma":[0.00002867138,0.0006891062,0.001068874,0.00000311514,0.00001390886,0.00005099517,0.00001127499,0.0006673631,0.9964843,0.00003629643,0.0009422262,0.000003870729],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954976,0.001648894,0.001356859,0.0001338316,0.00005888645,0.00002462272,0.000190717,0.0001023382,0.0009862429],"genre_scores_gemma":[0.9966435,0.00082717,0.001018099,0.00004049834,0.00001101168,0.00002086796,0.000194815,0.0000150538,0.001228994],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009549819,"threshold_uncertainty_score":0.003194749,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03072229735492715,"score_gpt":0.299576856829981,"score_spread":0.2688545594750539,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}