{"id":"W2128028685","doi":"10.1073/pnas.1503688112","title":"A ΩX <i>a</i> V motif in the Rift Valley fever virus NSs protein is essential for degrading p62, forming nuclear filaments and virulence","year":2015,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Viral Infections and Vectors","field":"Medicine","cited_by":39,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"Office of Extramural Research, National Institutes of Health; Natural Sciences and Engineering Research Council of Canada; National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; National Institutes of Health; Government of Canada","keywords":"Biology; Virulence; Transcription factor II H; Virology; Protein subunit; Nuclear protein; Virus; Bunyaviridae; Cell biology; Transcription factor; Genetics; Gene; DNA repair; Nucleotide excision repair","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001315048,0.0002713848,0.0002392439,0.0001006801,0.000186654,0.0002275629,0.0001883476,0.0003573152,0.0007824968],"category_scores_gemma":[0.000245627,0.0001407821,0.0003728338,0.00009375394,0.000203965,0.0001722405,0.0001787731,0.0003645292,0.0004855615],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002619297,"about_ca_system_score_gemma":0.000151714,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004507904,"about_ca_topic_score_gemma":0.0003801424,"domain_scores_codex":[0.9998606,0.00003691466,0.00001611203,0.00002786677,0.00003643542,0.0000219977],"domain_scores_gemma":[0.9998299,0.00002881421,0.00006961043,0.00001765343,0.00001280077,0.00004127075],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009298942,0.00001794276,0.0005197104,0.00002200707,0.000006937072,0.0001389883,0.00001182338,0.0001484287,0.9978879,0.0001092257,0.00002741397,0.001016573],"study_design_scores_gemma":[0.00003498818,0.0004715646,0.01828131,0.00001959069,0.0000227381,0.001190522,0.00005131393,0.002545696,0.9740015,0.0001631951,0.003201641,0.00001609448],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9941965,0.0003356591,0.004767152,0.00005099113,0.00002164723,0.00001644717,0.0001013239,0.00005959961,0.000450605],"genre_scores_gemma":[0.9965441,0.00009454029,0.002645231,0.00003634984,0.000007934565,0.00001040063,0.0002133855,0.00001254223,0.0004355648],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007824968,"threshold_uncertainty_score":0.002617717,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07203235192803945,"score_gpt":0.3374570852425691,"score_spread":0.2654247333145296,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}