{"id":"W2128028685","doi":"10.1073/pnas.1503688112","title":"A ΩX <i>a</i> V motif in the Rift Valley fever virus NSs protein is essential for degrading p62, forming nuclear filaments and virulence","year":2015,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Viral Infections and Vectors","field":"Medicine","cited_by":39,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"Office of Extramural Research, National Institutes of Health; Natural Sciences and Engineering Research Council of Canada; National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; National Institutes of Health; Government of Canada","keywords":"Biology; Virulence; Transcription factor II H; Virology; Protein subunit; Nuclear protein; Virus; Bunyaviridae; Cell biology; Transcription factor; Genetics; Gene; DNA repair; Nucleotide excision repair","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00139078,0.00007828696,0.0001320859,0.0001294152,0.0001947228,0.00003390205,0.0002715307,0.00005948407,0.000005328653],"category_scores_gemma":[0.0004532142,0.00004438775,0.00005412976,0.0004790366,0.0003616876,0.0004339983,0.00007115368,0.0001414784,5.969969e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003303183,"about_ca_system_score_gemma":0.00003234992,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005455103,"about_ca_topic_score_gemma":4.4487e-7,"domain_scores_codex":[0.9987677,0.000005295782,0.0002285585,0.0001780111,0.0006793435,0.0001410297],"domain_scores_gemma":[0.9995465,0.0000485336,0.0001966035,0.000008646211,0.0001626834,0.00003704441],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001723062,0.0003143339,0.02944166,0.0003201744,0.00004743431,4.97263e-8,0.005014488,0.00003186823,0.9191034,0.03946324,0.004379332,0.001711649],"study_design_scores_gemma":[0.003868967,0.00106987,0.1167673,0.001484694,0.0001421128,0.0001262861,0.005633981,0.0271752,0.7502559,0.08704185,0.005996288,0.0004374554],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.99482,0.00007113237,0.000003814699,0.003189974,0.00001647783,0.0005233713,0.000008203659,0.000006635609,0.001360422],"genre_scores_gemma":[0.9977292,0.00001320413,0.001496792,0.0005916529,0.00005528192,0.00002684947,8.912445e-8,0.000004292184,0.00008260969],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1688475,"threshold_uncertainty_score":0.181008,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07203235192803945,"score_gpt":0.3374570852425691,"score_spread":0.2654247333145296,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}