{"id":"W2128059069","doi":"10.1210/en.2003-1768","title":"Transgenic Mice Expressing Fibroblast Growth Factor 23 under the Control of the α1(I) Collagen Promoter Exhibit Growth Retardation, Osteomalacia, and Disturbed Phosphate Homeostasis","year":2004,"lang":"en","type":"article","venue":"Endocrinology","topic":"Parathyroid Disorders and Treatments","field":"Medicine","cited_by":501,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Montreal Children's Hospital","funders":"Karolinska Institutet","keywords":"Internal medicine; Endocrinology; Fibroblast growth factor 23; Hypophosphatemia; Osteomalacia; Genetically modified mouse; PHEX; Rickets; Transgene; Fibroblast growth factor; Homeostasis; Biology; Chemistry; Parathyroid hormone; Vitamin D and neurology; Calcium; Medicine; Biochemistry; Receptor; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002115599,0.001308891,0.0004545176,0.0008665092,0.0002094116,0.0004283215,0.0004171984,0.0007639971,0.002579892],"category_scores_gemma":[0.000187602,0.0004577732,0.0004956108,0.0003456583,0.0006054525,0.0002505665,0.0002890627,0.001135015,0.00118606],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003406784,"about_ca_system_score_gemma":0.0002018598,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008255973,"about_ca_topic_score_gemma":0.001633127,"domain_scores_codex":[0.9996524,0.00003786386,0.00003699119,0.00009181604,0.0001119415,0.00006910712],"domain_scores_gemma":[0.9995155,0.00005816604,0.0002201753,0.00002845881,0.00002529765,0.0001524444],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001146502,0.00003444049,0.0002837963,0.00001585022,0.00001158776,0.0001489809,0.00001820266,0.00003164629,0.9983418,0.00008757792,0.00005407063,0.0008575086],"study_design_scores_gemma":[0.0001782743,0.0008344438,0.0182675,0.00003007681,0.0001570517,0.005818707,0.0000891205,0.001278725,0.9666988,0.0002092261,0.006404178,0.00003386758],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9870493,0.001705392,0.006607919,0.0001616042,0.00007277002,0.00005345117,0.001746161,0.0007772788,0.00182611],"genre_scores_gemma":[0.9688545,0.002605588,0.009813501,0.0001719383,0.00006218041,0.0001812438,0.003612614,0.0003183308,0.01438012],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002579892,"threshold_uncertainty_score":0.008630633,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01286182065581101,"score_gpt":0.242002131714082,"score_spread":0.229140311058271,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}