{"id":"W2128100826","doi":"10.1200/jco.2001.19.3.881","title":"Aromatase Inhibitors in the Treatment and Prevention of Breast Cancer","year":2001,"lang":"en","type":"review","venue":"Journal of Clinical Oncology","topic":"Estrogen and related hormone effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":302,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre","funders":"","keywords":"Exemestane; Aromatase; Medicine; Letrozole; Anastrozole; Breast cancer; Tamoxifen; Oncology; Internal medicine; Adjuvant; Aromatase inhibitor; Clinical trial; Cancer; Hormonal therapy; Metastatic breast cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005301551,0.0002800726,0.0004463373,0.0007952535,0.0001363738,0.000474462,0.0002454336,0.0004137204,0.002024208],"category_scores_gemma":[0.0004549411,0.00008817872,0.0002582998,0.0008511571,0.0002395822,0.0002986348,0.0002494681,0.0007190878,0.0007867758],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002928313,"about_ca_system_score_gemma":0.0005504267,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004841125,"about_ca_topic_score_gemma":0.001143895,"domain_scores_codex":[0.9998122,0.00006414406,0.00002645446,0.00001793874,0.00006207553,0.00001719839],"domain_scores_gemma":[0.9998212,0.0000785697,0.00004251481,0.000007020475,0.00003527883,0.00001534239],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0005264225,0.0001616017,0.002114758,0.007882941,0.000164599,0.0006695526,0.00005113814,0.0004426349,0.006860814,0.003719671,0.01328389,0.9641219],"study_design_scores_gemma":[0.0001614013,0.001415444,0.01194264,0.004094276,0.0005314111,0.008553877,0.0001454448,0.0003427032,0.006391076,0.004487287,0.9619021,0.00003236905],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0007518106,0.9970213,0.0001571195,0.0007263378,0.0002045555,0.000004717449,0.00001612504,0.00000619604,0.001111845],"genre_scores_gemma":[0.01106232,0.9864465,0.0004602671,0.0003274913,0.0005189726,0.000005654146,0.00002706316,0.000002379112,0.001149319],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002024208,"threshold_uncertainty_score":0.006771624,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08670870874939896,"score_gpt":0.4863186828647579,"score_spread":0.399609974115359,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}