{"id":"W2128128123","doi":"10.1093/carcin/bgv031","title":"Causes of genome instability: the effect of low dose chemical exposures in modern society","year":2015,"lang":"en","type":"review","venue":"Carcinogenesis","topic":"Carcinogens and Genotoxicity Assessment","field":"Biochemistry, Genetics and Molecular Biology","cited_by":225,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; McMaster University Medical Centre; Health Canada","funders":"National Institute of Environmental Health Sciences; National Cancer Institute","keywords":"Genome instability; Epigenetics; Genome; Chromosome instability; Biology; Carcinogenesis; DNA damage; DNA repair; Genetics; Telomere; DNA; Chromosome; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0008608925,0.0004694199,0.001644976,0.00006710795,0.00003022501,0.00001057395,0.0005572315,0.0005393617,0.000006480136],"category_scores_gemma":[0.00007203675,0.0003133903,0.001181151,0.000270344,0.0002804565,0.000002602254,0.0004216376,0.0001875712,0.000001135591],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001072908,"about_ca_system_score_gemma":0.0005062954,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007303499,"about_ca_topic_score_gemma":0.00004047949,"domain_scores_codex":[0.9975965,0.0003806066,0.0007832231,0.0005809871,0.0003311725,0.0003274822],"domain_scores_gemma":[0.9982395,0.00008427889,0.0003799345,0.001053541,0.0001478538,0.00009486561],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002515909,0.0003737903,0.006249374,0.05739314,0.001398957,0.00001290605,0.000567587,0.0001753047,0.359372,0.000008252766,0.0003571062,0.57384],"study_design_scores_gemma":[0.004131075,0.002777733,0.00311616,0.004843547,0.004391413,0.0001236046,0.0003999092,0.00007861046,0.6078151,0.00004966226,0.3696976,0.002575591],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.3241301,0.6747994,0.00001702196,0.00000362767,0.00005317571,0.0007323634,0.0002285713,0.000003610142,0.00003206774],"genre_scores_gemma":[0.207504,0.7916924,0.00005079989,0.00001385043,0.0001459718,0.0001865086,0.000320935,0.00005743471,0.00002817705],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.5712644,"threshold_uncertainty_score":0.9999318,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02714455965392822,"score_gpt":0.3089666672474051,"score_spread":0.2818221075934769,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}