{"id":"W2128229230","doi":"10.1016/j.stem.2013.01.019","title":"Reactive Glia in the Injured Brain Acquire Stem Cell Properties in Response to Sonic Hedgehog","year":2013,"lang":"en","type":"article","venue":"Cell stem cell","topic":"Hedgehog Signaling Pathway Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":378,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université Laval; Institut Universitaire en Santé Mentale de Québec","funders":"National Institute of Neurological Disorders and Stroke; Howard Hughes Medical Institute","keywords":"Biology; Sonic hedgehog; Stem cell; Neurosphere; Neuroscience; Cell biology; Neural stem cell; Hedgehog signaling pathway; Adult stem cell; In vitro; Endothelial stem cell; Signal transduction","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001882978,0.0003917584,0.0002508484,0.0004451335,0.0002917823,0.0003609661,0.0002133655,0.0002580202,0.000929037],"category_scores_gemma":[0.0001287309,0.0002120177,0.0002726338,0.0002992834,0.0003624675,0.0003906776,0.000240723,0.0005446803,0.000332466],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002284864,"about_ca_system_score_gemma":0.0001794238,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001150939,"about_ca_topic_score_gemma":0.001593396,"domain_scores_codex":[0.9998734,0.00001765433,0.00001317327,0.00001733732,0.00003381529,0.00004449699],"domain_scores_gemma":[0.9999158,0.00001114871,0.00001814777,0.00001035467,0.00001918632,0.00002529835],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002180921,0.0000128416,0.0002948853,0.0000260536,0.000007563453,0.000189174,0.00004523925,0.00002441883,0.9979882,0.0002181765,0.00002433493,0.0009509727],"study_design_scores_gemma":[0.00001498097,0.00018938,0.01090541,0.000005504194,0.00003303392,0.0006200926,0.0001971241,0.0002667466,0.9866588,0.000200288,0.0009036016,0.000005062622],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9934102,0.001224227,0.002229478,0.00008152932,0.00003112134,0.00001672033,0.0002564897,0.00004439213,0.002705908],"genre_scores_gemma":[0.9926676,0.001094528,0.00164325,0.00005519233,0.0000173195,0.00003384552,0.0004024546,0.00001942869,0.004066489],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001150939,"threshold_uncertainty_score":0.003107905,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01706980089343616,"score_gpt":0.2240985109069379,"score_spread":0.2070287100135017,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}