{"id":"W2128247334","doi":"10.1128/aac.48.3.843-851.2004","title":"Selection of an Antibiotic-Hypersusceptible Mutant of <i>Pseudomonas aeruginosa</i> : Identification of the GlmR Transcriptional Regulator","year":2004,"lang":"en","type":"article","venue":"Antimicrobial Agents and Chemotherapy","topic":"Antibiotic Resistance in Bacteria","field":"Biochemistry, Genetics and Molecular Biology","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; Petroleum Technology Alliance Canada","keywords":"Biology; Pseudomonas aeruginosa; Mutant; Peptidoglycan; Microbiology; Transposable element; Transposon mutagenesis; Operon; Pyocyanin; Aminoglycoside; Antimicrobial peptides; Mutagenesis; Gene; Genetics; Antibiotics; Antimicrobial; Virulence; Quorum sensing; Bacteria","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001384488,0.0006130239,0.0003229528,0.0002606758,0.0001677909,0.0002364871,0.0004580316,0.000362853,0.001249472],"category_scores_gemma":[0.0002574793,0.0001965241,0.0004081116,0.000241442,0.0002171757,0.0001305231,0.0003796715,0.000531671,0.0008002422],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003103299,"about_ca_system_score_gemma":0.0002912167,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002248918,"about_ca_topic_score_gemma":0.002155747,"domain_scores_codex":[0.9997156,0.00005571848,0.00003054766,0.00005368644,0.00008866453,0.00005583092],"domain_scores_gemma":[0.9997669,0.00004741255,0.00006932238,0.00003193234,0.00003196766,0.00005249122],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002487078,0.00002533293,0.0001213034,0.00001151172,0.000002981613,0.00007532007,0.00000890236,0.00002306548,0.9991708,0.00003014359,0.00001917712,0.000486582],"study_design_scores_gemma":[0.00002382659,0.0004375422,0.01019493,0.00001215626,0.00002984796,0.00160793,0.0000649656,0.001605013,0.9832752,0.00003513633,0.002698243,0.00001512699],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9901832,0.0002536089,0.006286356,0.0001788768,0.00004115402,0.0001690492,0.0009828723,0.000193373,0.001711593],"genre_scores_gemma":[0.9820114,0.0003893843,0.01071897,0.0001602081,0.00002145715,0.0001380556,0.002441451,0.0002027402,0.00391624],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002248918,"threshold_uncertainty_score":0.004471719,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006864461547286723,"score_gpt":0.2293820988673569,"score_spread":0.2225176373200702,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}