{"id":"W2128252950","doi":"10.1016/j.biomaterials.2009.06.010","title":"The binding of pullulan modified cholesteryl nanogels to Aβ oligomers and their suppression of cytotoxicity","year":2009,"lang":"en","type":"article","venue":"Biomaterials","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":94,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"","keywords":"Pullulan; Cytotoxicity; Monomer; Oligomer; Biophysics; Chemistry; Amyloid (mycology); Amyloid beta; Biochemistry; Organic chemistry; In vitro; Polymer; Peptide; Biology; Polysaccharide","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001963694,0.0004353199,0.0002125401,0.0001334992,0.0001578666,0.0001979782,0.0001983646,0.0004034337,0.001090036],"category_scores_gemma":[0.0002083635,0.0001963192,0.0002834039,0.0000912865,0.0001968619,0.0003075363,0.0001861075,0.0003405774,0.0002999393],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002066568,"about_ca_system_score_gemma":0.0001649139,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005947194,"about_ca_topic_score_gemma":0.0007321621,"domain_scores_codex":[0.9998981,0.00001391518,0.00001308315,0.000020506,0.00002130445,0.00003299811],"domain_scores_gemma":[0.9999113,0.00002809287,0.00001855301,0.00001158378,0.00001539019,0.00001507151],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007173424,0.000009933033,0.00003261616,0.00002120642,0.000003160587,0.00002065991,0.00001239641,0.00002776958,0.9994662,0.0000302487,0.000008502423,0.0002954586],"study_design_scores_gemma":[0.000005509491,0.00008320927,0.0003961992,0.000002178006,0.000005138202,0.00004220639,0.000008492591,0.0001414895,0.9990172,0.00001155929,0.0002848145,0.000002020107],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9975412,0.0008381473,0.0009546526,0.00003612361,0.00001862358,0.0000123762,0.00005088439,0.00001028635,0.0005375986],"genre_scores_gemma":[0.9964321,0.0005577519,0.000870641,0.00005725733,0.000005996195,0.00002611976,0.0001256534,0.00001144746,0.001913137],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001090036,"threshold_uncertainty_score":0.003646553,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03305040010861479,"score_gpt":0.3140161260782786,"score_spread":0.2809657259696638,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}