{"id":"W2128264299","doi":"10.4049/jimmunol.177.12.8466","title":"Asynchronous Differentiation of CD8 T Cells That Recognize Dominant and Cryptic Antigens","year":2006,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute for Research in Immunology and Cancer; Centre Hospitalier Universitaire de Sherbrooke; Toronto General Hospital; Université de Montréal; Hôpital Maisonneuve-Rosemont","funders":"","keywords":"Biology; CD8; Effector; Cytotoxic T cell; Immunodominance; T cell; Epitope; Cell biology; Antigen; Antigen-presenting cell; Interleukin 21; Immune system; Streptamer; Immunology; Genetics; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001065863,0.0001259046,0.0001277524,0.0001526296,0.00008918811,0.0001962275,0.00009285018,0.000134837,0.0006174902],"category_scores_gemma":[0.0001283727,0.00009320333,0.0001190706,0.0001446058,0.0001154702,0.0001534602,0.0001438435,0.000381112,0.0003054293],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001422878,"about_ca_system_score_gemma":0.0001013609,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001902266,"about_ca_topic_score_gemma":0.0005188858,"domain_scores_codex":[0.9999073,0.000009967951,0.000006716647,0.000033233,0.00002091546,0.00002194616],"domain_scores_gemma":[0.9998717,0.00002978713,0.00002695417,0.00001572118,0.00002178662,0.00003397903],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008895594,0.000009752421,0.001358696,0.00001522797,0.000001805154,0.00001675012,0.00001952003,0.0000546845,0.996592,0.00004835823,0.00001406387,0.001780165],"study_design_scores_gemma":[0.00003142493,0.0004338351,0.03942644,0.00001186134,0.00002939771,0.0002357009,0.0001232319,0.003297064,0.9531693,0.0003466143,0.002887748,0.000007285637],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954379,0.0005061565,0.003217329,0.00002350146,0.000009819972,0.0000132848,0.0002069157,0.00003819061,0.0005468896],"genre_scores_gemma":[0.9948629,0.0002544149,0.003046526,0.00006211884,0.00001156024,0.00003199285,0.000436863,0.00002125583,0.001272384],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006174902,"threshold_uncertainty_score":0.002065778,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0090774134840599,"score_gpt":0.2030648021851594,"score_spread":0.1939873887010995,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}