{"id":"W2128311713","doi":"10.1093/jac/dki288","title":"Activity of posaconazole in the treatment of central nervous system fungal infections","year":2005,"lang":"en","type":"article","venue":"Journal of Antimicrobial Chemotherapy","topic":"Fungal Infections and Studies","field":"Medicine","cited_by":250,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"King Faisal Specialist Hospital and Research Centre; School of Medicine, New York University; York University; Cleveland Clinic Foundation; Cleveland Clinic","keywords":"Posaconazole; Medicine; Aspergillosis; Coccidioides; Internal medicine; Coccidioides immitis; Mycosis; Meningitis; Immunology; Itraconazole; Antifungal; Surgery; Dermatology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001493479,0.0001075006,0.0004352278,0.0001432381,0.0000462422,0.000006669472,0.00005296234,0.00005415014,0.00001946371],"category_scores_gemma":[0.000006765768,0.00006466019,0.0002795522,0.0001959002,0.00006512296,0.00007044158,0.000003328528,0.0001239709,8.230762e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001723387,"about_ca_system_score_gemma":0.00008850071,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001427377,"about_ca_topic_score_gemma":0.00006694477,"domain_scores_codex":[0.9992192,0.0000483298,0.0003996203,0.00006395796,0.0001270434,0.0001418951],"domain_scores_gemma":[0.9993493,0.00006055072,0.0003057033,0.0001150933,0.0001359652,0.00003337609],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001648568,0.00911634,0.1093359,0.0002083095,0.0007963381,0.0000468234,0.005624509,0.0006767423,0.8453053,0.0001035999,0.002667882,0.02446974],"study_design_scores_gemma":[0.007307526,0.004650283,0.3624168,0.000341406,0.0002293148,0.001720055,0.0006059581,0.0001455242,0.6113418,0.000002908801,0.01110666,0.000131735],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9965879,0.0002411965,0.00006848834,0.002119454,0.0001735442,0.0001754663,0.000009500407,0.000005139312,0.0006193288],"genre_scores_gemma":[0.9982187,0.001040387,0.0002404004,0.0001181809,0.0003232999,0.000001092598,4.937743e-7,0.000008688033,0.00004882733],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2530809,"threshold_uncertainty_score":0.2636766,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.013082027801233,"score_gpt":0.2692671539239226,"score_spread":0.2561851261226896,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}