{"id":"W2128311713","doi":"10.1093/jac/dki288","title":"Activity of posaconazole in the treatment of central nervous system fungal infections","year":2005,"lang":"en","type":"article","venue":"Journal of Antimicrobial Chemotherapy","topic":"Fungal Infections and Studies","field":"Medicine","cited_by":250,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"King Faisal Specialist Hospital and Research Centre; School of Medicine, New York University; York University; Cleveland Clinic Foundation; Cleveland Clinic","keywords":"Posaconazole; Medicine; Aspergillosis; Coccidioides; Internal medicine; Coccidioides immitis; Mycosis; Meningitis; Immunology; Itraconazole; Antifungal; Surgery; Dermatology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00167683,0.0004183516,0.0007459661,0.0001444096,0.0001704429,0.0004514306,0.0003359505,0.0004610241,0.001553175],"category_scores_gemma":[0.001197744,0.0001415772,0.0003536917,0.0002214563,0.0004453651,0.000386741,0.000173922,0.001071693,0.0001627682],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003591508,"about_ca_system_score_gemma":0.0006888,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004372187,"about_ca_topic_score_gemma":0.001156016,"domain_scores_codex":[0.9995504,0.0002761307,0.00004355295,0.00005025891,0.00003970812,0.00003994178],"domain_scores_gemma":[0.9993464,0.0001937889,0.0002036643,0.00004140605,0.00006517379,0.0001494929],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.6888606,0.01844196,0.02046754,0.002217182,0.001368094,0.0003459143,0.0002028063,0.00155078,0.03869919,0.0002430628,0.0009362008,0.2266666],"study_design_scores_gemma":[0.3276033,0.5778772,0.07581677,0.0003103594,0.00116417,0.00089053,0.0001208553,0.002251838,0.01067743,0.0001896292,0.003063409,0.00003440771],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9952264,0.003592734,0.0001184349,0.0001782669,0.0000404419,0.000220696,0.00009502421,0.00001261783,0.0005154263],"genre_scores_gemma":[0.9976838,0.001488527,0.0002404336,0.0001151829,0.0000430756,0.0001119238,0.0001080048,0.000001604796,0.0002074061],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00167683,"threshold_uncertainty_score":0.008868039,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.013082027801233,"score_gpt":0.2692671539239226,"score_spread":0.2561851261226896,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}