{"id":"W2128312247","doi":"10.1152/ajpendo.00044.2013","title":"Both aerobic exercise and resveratrol supplementation attenuate doxorubicin-induced cardiac injury in mice","year":2013,"lang":"en","type":"article","venue":"American Journal of Physiology-Endocrinology and Metabolism","topic":"Chemotherapy-induced cardiotoxicity and mitigation","field":"Medicine","cited_by":139,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; Children's Hospital Research Institute of Manitoba; University of Alberta","funders":"National Cancer Institute; Canadian Institutes of Health Research; University of Alberta","keywords":"Cardiotoxicity; Doxorubicin; Medicine; Heart failure; Resveratrol; Pharmacology; Oxidative stress; Aerobic exercise; Lipid peroxidation; Apoptosis; Superoxide dismutase; Internal medicine; Endocrinology; Chemotherapy; Chemistry; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001995143,0.0002076381,0.0009439692,0.0003145578,0.00007449734,0.00001347912,0.00007522405,0.00008138365,0.00004369421],"category_scores_gemma":[0.00003625164,0.0001744377,0.0001265021,0.0002108727,0.0003648928,0.0002523752,0.00003819086,0.000514826,0.000005863254],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003559487,"about_ca_system_score_gemma":0.00007840042,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003705815,"about_ca_topic_score_gemma":0.000004825945,"domain_scores_codex":[0.9984912,0.0002590282,0.0004829182,0.0002678026,0.0001239681,0.0003751347],"domain_scores_gemma":[0.9990951,0.00008529136,0.0003723783,0.0001514229,0.0001387678,0.0001570314],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0004392197,0.00005433053,0.001727938,0.00001802942,0.0001632201,0.00000808132,0.0005759983,0.000001235726,0.913254,0.000130637,0.0002953363,0.08333201],"study_design_scores_gemma":[0.003207803,0.0007851921,0.5474483,0.00008178927,0.0002909845,0.0002518694,0.001922508,0.000007910165,0.4441542,0.0006860151,0.0009760993,0.0001873338],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9960268,0.001481668,0.000009229448,0.001755237,0.0002724577,0.0003726454,0.000005715379,0.00001281227,0.00006339668],"genre_scores_gemma":[0.9908615,0.006957655,0.0007084019,0.001099229,0.0002817771,0.00002760436,0.000008778805,0.00001828451,0.00003682323],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5457203,"threshold_uncertainty_score":0.7113364,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008128678544329554,"score_gpt":0.2601130185174484,"score_spread":0.2519843399731189,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}