{"id":"W2128314339","doi":"10.2967/jnumed.108.051771","title":"Trastuzumab-Resistant Breast Cancer Cells Remain Sensitive to the Auger Electron–Emitting Radiotherapeutic Agent <sup>111</sup>In-NLS-Trastuzumab and Are Radiosensitized by Methotrexate","year":2008,"lang":"en","type":"article","venue":"Journal of Nuclear Medicine","topic":"Radiopharmaceutical Chemistry and Applications","field":"Medicine","cited_by":87,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network; University of Toronto","funders":"Connaught Fund; Genentech; Cancer Research UK; Canadian Institutes of Health Research; Canadian Breast Cancer Research Alliance","keywords":"Trastuzumab; Chemistry; Breast cancer; Cancer; Medicine; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001178084,0.0002078546,0.0003406253,0.00008386718,0.0001474292,0.0003469139,0.0001793199,0.0002434312,0.001274546],"category_scores_gemma":[0.0001355393,0.0001203116,0.0001308146,0.0001386521,0.0002033859,0.0001773999,0.0001394576,0.0002759779,0.0004235136],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004025819,"about_ca_system_score_gemma":0.0001367118,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006174449,"about_ca_topic_score_gemma":0.0006599592,"domain_scores_codex":[0.9998271,0.00002581715,0.00001343588,0.00002920008,0.00006472085,0.00003977723],"domain_scores_gemma":[0.9998631,0.00002767425,0.00004506125,0.00002437321,0.00002523222,0.00001451335],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007358289,0.00001363891,0.0004768442,0.00002161613,0.000005308077,0.0000549387,0.00001900069,0.0000615502,0.9983529,0.00004412058,0.00002752262,0.000848951],"study_design_scores_gemma":[0.00001152426,0.0001536518,0.006445604,0.000003500274,0.00001242424,0.0003607245,0.00003118656,0.0003332306,0.9906054,0.00001961074,0.002020684,0.000002383422],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9957964,0.001273688,0.001297014,0.00006691953,0.0000096565,0.00001897618,0.00009478503,0.00004931749,0.001393186],"genre_scores_gemma":[0.9956488,0.0005847903,0.00096514,0.00005214306,0.000006871711,0.00002113435,0.0003342171,0.00001480679,0.00237218],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001274546,"threshold_uncertainty_score":0.004263818,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01973195364876909,"score_gpt":0.3018636027027358,"score_spread":0.2821316490539666,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}