{"id":"W2128381931","doi":"10.1186/1476-511x-10-144","title":"In vitro cytotoxicity of two novel oral formulations of Amphotericin B (iCo-009 and iCo-010) against Candida albicans, human monocytic and kidney cell lines","year":2011,"lang":"en","type":"article","venue":"Lipids in Health and Disease","topic":"Antifungal resistance and susceptibility","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"British Columbia Institute of Technology; iCo Therapeutics (Canada); University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Cytotoxicity; Amphotericin B; Nephrotoxicity; Candida albicans; In vivo; Corpus albicans; Pharmacology; In vitro; Microbiology; Biology; Cytotoxic T cell; Kidney; Antifungal; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000227188,0.0002679816,0.0002361248,0.0001486425,0.0001155059,0.0002143026,0.0001591746,0.0002443136,0.0008028196],"category_scores_gemma":[0.0001975927,0.00009919037,0.0001726792,0.0002066744,0.0001556212,0.0001249421,0.0001197575,0.0002997395,0.0001579249],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001642412,"about_ca_system_score_gemma":0.0002216124,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007485318,"about_ca_topic_score_gemma":0.0009254576,"domain_scores_codex":[0.9998307,0.00003296223,0.00002817297,0.00002738896,0.00006288161,0.00001778401],"domain_scores_gemma":[0.9998468,0.00005031026,0.00004166606,0.000009927012,0.00003200533,0.00001917658],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007370711,0.0001868691,0.0005169645,0.0003102196,0.00001591654,0.0001094438,0.0000646156,0.0003775173,0.9928295,0.00006383529,0.0001268635,0.004661239],"study_design_scores_gemma":[0.0001143803,0.005173233,0.007462599,0.00005069234,0.00007673493,0.000687301,0.00007375221,0.0009700265,0.9820898,0.00002650225,0.003257042,0.00001805172],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9903027,0.007051304,0.000723405,0.00006517569,0.0000396717,0.00003963056,0.0003866724,0.00001248829,0.001378935],"genre_scores_gemma":[0.9896005,0.004982997,0.002929515,0.00004911859,0.00001994279,0.00006190281,0.0007478152,0.000005929561,0.001602243],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008028196,"threshold_uncertainty_score":0.002685666,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04350528159362954,"score_gpt":0.3255834409376159,"score_spread":0.2820781593439863,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}