{"id":"W2128410902","doi":"10.2174/092986707782793952","title":"Autoimmunity and Apoptosis - Therapeutic Implications","year":2007,"lang":"en","type":"review","venue":"Current Medicinal Chemistry","topic":"Hepatitis Viruses Studies and Epidemiology","field":"Medicine","cited_by":49,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; CancerCare Manitoba; Victoria General Hospital","funders":"Canadian Institutes of Health Research; CancerCare Manitoba Foundation; Manitoba Health Research Council","keywords":"Autoimmunity; Immune system; Immunology; Biology; Peripheral tolerance; Clonal deletion; Immune tolerance; Central tolerance; Autoantibody; Self Tolerance; Acquired immune system; Innate immune system; T cell; T-cell receptor; Antibody","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006098618,0.0007177715,0.001267704,0.001913477,0.0003118213,0.000919534,0.000799055,0.001372156,0.003185568],"category_scores_gemma":[0.0006133789,0.0001924323,0.0003881229,0.001481389,0.0007320121,0.001315396,0.00064271,0.002068783,0.001814732],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007580558,"about_ca_system_score_gemma":0.0005767225,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004700896,"about_ca_topic_score_gemma":0.001098484,"domain_scores_codex":[0.9997962,0.00004551525,0.00002516052,0.00003596836,0.00007513191,0.0000220509],"domain_scores_gemma":[0.9997074,0.0001418517,0.00003302569,0.00001606091,0.00006803985,0.00003354532],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009657962,0.0001130606,0.000219235,0.006920562,0.00005326608,0.0003903647,0.00008754681,0.000389209,0.002477082,0.008525663,0.03103714,0.9496903],"study_design_scores_gemma":[0.0000313051,0.0001116265,0.0009264809,0.002037642,0.00003939675,0.002476296,0.00007201048,0.0001010131,0.0008094623,0.00623555,0.9871433,0.00001576938],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000123243,0.9982045,0.00008935744,0.0003942485,0.000225273,0.000002144584,0.000005230311,0.000005130811,0.000950938],"genre_scores_gemma":[0.001502559,0.996472,0.0001747192,0.000416498,0.0003338885,0.000006589729,0.00001548026,0.000001511761,0.00107677],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003185568,"threshold_uncertainty_score":0.01065677,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2570238650313537,"score_gpt":0.4692054620443069,"score_spread":0.2121815970129532,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}