{"id":"W2128446472","doi":"10.1016/j.abb.2012.07.010","title":"Molecular cloning and characterization of (+)-epi-α-bisabolol synthase, catalyzing the first step in the biosynthesis of the natural sweetener, hernandulcin, in Lippia dulcis","year":2012,"lang":"en","type":"article","venue":"Archives of Biochemistry and Biophysics","topic":"Plant biochemistry and biosynthesis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":58,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary","funders":"Canada Research Chairs; Genome Canada","keywords":"Sesquiterpene; Biosynthesis; Biochemistry; ATP synthase; Farnesyl diphosphate synthase; Chemistry; Yeast; Streptomyces clavuligerus; Enzyme; Biology; Stereochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002228529,0.0001943604,0.0002284334,0.00002489204,0.00007524018,0.00001070466,0.0003765556,0.0001164841,6.682765e-7],"category_scores_gemma":[0.0001361496,0.0001135461,0.0001054347,0.0001868679,0.0005208421,0.00001156876,0.0002021621,0.0001455361,5.600257e-8],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000003475664,"about_ca_system_score_gemma":0.00002895934,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005968021,"about_ca_topic_score_gemma":0.00001220492,"domain_scores_codex":[0.9989938,0.00007979717,0.0003273998,0.000233792,0.0001376458,0.0002276338],"domain_scores_gemma":[0.9991306,0.0001470331,0.0002779289,0.0003868377,0.00002536297,0.00003220689],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001055244,0.0001208887,0.02089032,0.0002308666,0.00003963329,6.954508e-7,0.0003073507,0.000001841272,0.9760147,0.00003342097,0.00000423637,0.002250534],"study_design_scores_gemma":[0.0002088128,0.00002663878,0.04679247,0.0002193436,0.00003731026,0.00001369167,0.0002929466,0.00007388359,0.9520712,0.00001710781,0.0001128847,0.0001337371],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997915,0.00136188,0.00001315799,0.0002791329,0.00003890654,0.0001481789,0.0001287767,0.000001991328,0.000113028],"genre_scores_gemma":[0.9991747,0.000505426,0.0000661152,0.00006616118,0.0000853887,0.000009262484,0.00006839947,0.000009379261,0.00001523079],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02590215,"threshold_uncertainty_score":0.4630278,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004243345669164037,"score_gpt":0.1905488103098343,"score_spread":0.1863054646406703,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}