{"id":"W2128493854","doi":"10.1189/jlb.1003498","title":"Phosphatase inhibition potentiates IL-6 production by mast cells in response to FcɛRI-mediated activation: involvement of p38 MAPK","year":2004,"lang":"en","type":"article","venue":"Journal of Leukocyte Biology","topic":"Mast cells and histamine","field":"Immunology and Microbiology","cited_by":56,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"Canadian Institutes of Health Research; Nova Scotia Health Research Foundation","keywords":"Biology; Mast cell; MAPK/ERK pathway; p38 mitogen-activated protein kinases; Protein phosphatase 2; Cell biology; Secretion; Interleukin 33; Immunoglobulin E; Phosphatase; Kinase; Phosphorylation; Protein kinase A; Cytokine; Molecular biology; Immunology; Antibody; Interleukin; Endocrinology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008096133,0.0001577079,0.000382892,0.0003936385,0.00005587438,0.000005686809,0.0001305608,0.0002309097,0.0002364157],"category_scores_gemma":[0.0001783068,0.0001348892,0.0000832948,0.0002664293,0.0001445775,0.000121153,0.00004941049,0.000288527,0.00006420264],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002298437,"about_ca_system_score_gemma":0.0001650347,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001470311,"about_ca_topic_score_gemma":0.00003911703,"domain_scores_codex":[0.9984287,0.0002621182,0.0007873262,0.0002123616,0.00005156216,0.0002579128],"domain_scores_gemma":[0.9988983,0.0000904139,0.0006038244,0.0001551146,0.0002097229,0.00004257821],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00451359,0.0004119955,0.0004237397,0.00002385815,0.00006528707,0.00001274654,0.0003853459,0.0001688693,0.989509,0.00008318463,0.003690022,0.0007123211],"study_design_scores_gemma":[0.002933522,0.00144724,0.003152346,0.0001059898,0.0000196547,0.00005105669,0.0002677524,3.784988e-7,0.9411925,0.0001129142,0.05059431,0.0001223241],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9948871,0.001487783,0.0003526649,0.002032908,0.0008941943,0.0002182535,0.0000949904,0.00000852653,0.00002353723],"genre_scores_gemma":[0.9985711,0.0002742323,0.0002900475,0.0002427828,0.00006544244,0.000006136727,0.0002118926,0.00001128719,0.000327097],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04831653,"threshold_uncertainty_score":0.5500621,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009547561497772106,"score_gpt":0.221968829841334,"score_spread":0.2124212683435619,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}