{"id":"W2128580831","doi":"10.1038/ncomms8251","title":"Structural insights into the translational infidelity mechanism","year":2015,"lang":"en","type":"article","venue":"Nature Communications","topic":"RNA and protein synthesis mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":137,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Nautical Research Society","funders":"Kazan Federal University; Agence Nationale de la Recherche; Aarhus Universitet","keywords":"Transfer RNA; Ribosome; Tautomer; Translation (biology); Decoding methods; Duplex (building); Genetic code; Genetics; Biology; Computational biology; DNA; Chemistry; Messenger RNA; RNA; Stereochemistry; Algorithm; Computer science; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002460682,0.00009764967,0.00007005227,0.00002205608,0.0002885569,0.00002772574,0.0009306158,0.0002588118,0.00000858216],"category_scores_gemma":[0.0001411573,0.00006810688,0.00006022493,0.00009788058,0.00009459913,0.000006343781,0.0002008591,0.0002964601,0.00001149081],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001041508,"about_ca_system_score_gemma":0.0001073111,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002640818,"about_ca_topic_score_gemma":0.0002871943,"domain_scores_codex":[0.9992483,0.0002062148,0.0001435138,0.0001465012,0.000159609,0.00009586518],"domain_scores_gemma":[0.9983624,0.00004037728,0.00005632088,0.001290379,0.000185233,0.00006527495],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007823098,0.00005733287,0.0007072266,0.00000683206,0.0001202543,5.01774e-7,0.002604833,0.00006675239,0.5056486,0.4769861,0.005769119,0.007954255],"study_design_scores_gemma":[0.0006339701,0.0001094493,0.002359035,0.00001265331,0.00004470503,0.00001625875,0.0005470832,0.001060077,0.2238254,0.1865977,0.5844043,0.0003893271],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8940157,0.05004342,0.007817337,0.03592566,0.0008071357,0.0008813639,0.00002654537,0.0000817601,0.01040103],"genre_scores_gemma":[0.9895995,0.0002769445,0.008920069,0.000770064,0.00009992041,0.00004110218,0.0001750798,0.00001081766,0.0001064874],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5786352,"threshold_uncertainty_score":0.2777318,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02891229004280831,"score_gpt":0.2979637752320651,"score_spread":0.2690514851892568,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}