{"id":"W2128636134","doi":"10.1084/jem.20010898","title":"Major Histocompatibility Complex Class II Presentation of Cell-associated Antigen Is Mediated by CD8α+ Dendritic Cells In Vivo","year":2002,"lang":"en","type":"article","venue":"The Journal of Experimental Medicine","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":63,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Antigen presentation; Antigen-presenting cell; Antigen; Cytotoxic T cell; Adoptive cell transfer; Biology; CD40; CD8; Priming (agriculture); Major histocompatibility complex; T cell; Cell biology; Immunology; Molecular biology; Immune system; In vitro; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002039204,0.0003946241,0.0001794578,0.0001880585,0.0001703032,0.0004477292,0.0001334046,0.0002529274,0.001454383],"category_scores_gemma":[0.0001853397,0.0001631209,0.000111178,0.0000833344,0.000187199,0.0002171467,0.0001388332,0.0005392678,0.001163081],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002511166,"about_ca_system_score_gemma":0.0002063286,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001936632,"about_ca_topic_score_gemma":0.0001502393,"domain_scores_codex":[0.9998515,0.00002714894,0.00001039944,0.00003282977,0.00003236663,0.00004579373],"domain_scores_gemma":[0.9998623,0.00001695578,0.00002803355,0.00002600998,0.00001963483,0.0000470671],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000143372,0.00004737814,0.0002288997,0.00002845834,0.000002477279,0.00003896398,0.00001178919,0.00004307108,0.9960998,0.0002142735,0.00008928026,0.003052199],"study_design_scores_gemma":[0.0001021681,0.00041716,0.001840647,0.00001126627,0.0000121796,0.0004249455,0.00002129207,0.001037174,0.9901401,0.0004448567,0.005545026,0.000003141929],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9748649,0.002332394,0.01473621,0.0003838125,0.0001409517,0.00008354029,0.0002885596,0.0002986245,0.006871038],"genre_scores_gemma":[0.9898072,0.00126786,0.003504037,0.00007935337,0.00004266056,0.00003481389,0.0002690615,0.00003683762,0.004958148],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001454383,"threshold_uncertainty_score":0.004865408,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02380718008028796,"score_gpt":0.2795196176346079,"score_spread":0.2557124375543199,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}