{"id":"W2128636134","doi":"10.1084/jem.20010898","title":"Major Histocompatibility Complex Class II Presentation of Cell-associated Antigen Is Mediated by CD8α+ Dendritic Cells In Vivo","year":2002,"lang":"en","type":"article","venue":"The Journal of Experimental Medicine","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":63,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Antigen presentation; Antigen-presenting cell; Antigen; Cytotoxic T cell; Adoptive cell transfer; Biology; CD40; CD8; Priming (agriculture); Major histocompatibility complex; T cell; Cell biology; Immunology; Molecular biology; Immune system; In vitro; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0007154128,0.0001789712,0.0005379754,0.0001565501,0.000153167,0.000002616839,0.0003531809,0.0001280736,0.006756859],"category_scores_gemma":[0.0000859687,0.0001183021,0.00009036746,0.0002071525,0.0005591139,0.0001050855,0.00004851766,0.0003184855,0.00001890397],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00014392,"about_ca_system_score_gemma":0.00002362442,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003800819,"about_ca_topic_score_gemma":0.000007469793,"domain_scores_codex":[0.9977607,0.0008055199,0.0009298599,0.0001108109,0.0001414751,0.0002516097],"domain_scores_gemma":[0.9984948,0.0005008605,0.0006631706,0.0002139523,0.0001024174,0.00002479102],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009667948,0.0009687013,0.0004879374,0.000008586877,0.0001364953,0.000003471922,0.01204968,0.000001150938,0.9407229,0.00000239968,0.0445787,0.0000731559],"study_design_scores_gemma":[0.00638699,0.002020883,0.002473234,0.0001225195,0.00004623291,0.00004725455,0.004035775,0.00003345121,0.9798734,0.000009115874,0.004846887,0.0001042443],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9619668,0.03592767,0.00001062861,0.0008056475,0.0004566871,0.0002977467,0.00003083191,0.00000774015,0.0004962303],"genre_scores_gemma":[0.9973099,0.0008892985,0.00001347659,0.0003591808,0.00001997397,0.000003658488,0.00001563619,0.00001460505,0.00137424],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03973182,"threshold_uncertainty_score":0.9941511,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02380718008028796,"score_gpt":0.2795196176346079,"score_spread":0.2557124375543199,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}