{"id":"W2128653564","doi":"","title":"Targeted liposomal c-myc antisense oligodeoxynucleotides induce apoptosis and inhibit tumor growth and metastases in human melanoma models.","year":2003,"lang":"en","type":"article","venue":"PubMed","topic":"Neuroblastoma Research and Treatments","field":"Medicine","cited_by":80,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"In vivo; Melanoma; In vitro; Cancer research; Liposome; Oncogene; Neuroblastoma; Cationic liposome; Apoptosis; Monoclonal antibody; Medicine; Pharmacology; Biology; Immunology; Cell culture; Antibody; Transfection; Biochemistry; Cell cycle","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002030075,0.0002308834,0.0003901195,0.0003399715,0.0001042865,0.00005786667,0.00004646195,0.00005315775,0.00001111997],"category_scores_gemma":[0.0002623585,0.000196847,0.0000468425,0.0003048135,0.0001459565,0.0002542883,0.00006554952,0.0002167863,0.000002757219],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003926494,"about_ca_system_score_gemma":0.00002951441,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001733427,"about_ca_topic_score_gemma":0.00002957331,"domain_scores_codex":[0.9982547,0.0001531961,0.0002590296,0.0004456579,0.0002783761,0.0006090348],"domain_scores_gemma":[0.9991665,0.00008122342,0.00005583659,0.0001910206,0.00004510287,0.0004602457],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002724771,0.005836337,0.6638476,0.0016679,0.001697675,0.008784726,0.001275588,0.00001622979,0.2330262,0.02367726,0.001060394,0.05638526],"study_design_scores_gemma":[0.006623407,0.000411823,0.4754387,0.00005955245,0.0001499953,0.0004833482,0.00009343553,0.00006244416,0.514312,0.002025208,0.00004274771,0.0002973205],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9956309,0.0006513774,0.000002726508,0.0002381811,0.00002644785,0.001015917,0.00002793452,0.0000511681,0.0023553],"genre_scores_gemma":[0.9988362,0.0001358823,0.0003059725,0.0001660961,0.0000221438,0.0003977285,0.00001310023,0.00003675932,0.00008610549],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2812859,"threshold_uncertainty_score":0.8027189,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02716445340812738,"score_gpt":0.2434002716511696,"score_spread":0.2162358182430422,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}