{"id":"W2128670961","doi":"10.1373/clinchem.2012.199711","title":"Evolving Role of Microparticles in the Pathophysiology of Endothelial Dysfunction","year":2013,"lang":"en","type":"review","venue":"Clinical Chemistry","topic":"Extracellular vesicles in disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":116,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; St. Michael's Hospital","funders":"","keywords":"Endothelial dysfunction; Endothelium; Inflammation; Endothelial stem cell; Proinflammatory cytokine; Angiogenesis; Population; Medicine; Immunology; Endothelial activation; Biology; Cancer research; Internal medicine; In vitro; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004874529,0.0002155659,0.0007755485,0.00001357094,0.00001448994,0.00000602143,0.000550084,0.0005564305,0.00005506483],"category_scores_gemma":[0.0008210642,0.0001540944,0.0005949749,0.00008388705,0.0003303804,0.000001988713,0.0001769789,0.0003193733,0.00001114856],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000009131522,"about_ca_system_score_gemma":0.0001756928,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003443853,"about_ca_topic_score_gemma":4.499915e-7,"domain_scores_codex":[0.9979374,0.0003049165,0.001082768,0.0003856066,0.0001065494,0.0001827735],"domain_scores_gemma":[0.9983193,0.0002196083,0.0005893222,0.0007480403,0.00007003144,0.00005372529],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00004298235,0.0005499614,0.0005444881,0.006593043,0.0001176811,0.000005263717,0.00001133895,9.811494e-7,0.5567583,0.00000864151,0.0006149925,0.4347523],"study_design_scores_gemma":[0.0008553906,0.0002711439,0.0001315571,0.002382857,0.0006545345,0.00002448058,0.000124149,0.00001889422,0.2052971,0.0006191427,0.789073,0.0005477281],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.122149,0.877207,0.000004112479,0.000003996236,0.00006394155,0.0002365883,0.00006566261,0.000003004709,0.0002667085],"genre_scores_gemma":[0.04402174,0.9549969,0.000144908,0.00002311272,0.0004397642,0.0000612656,0.0001826596,0.00002953185,0.0001001526],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.788458,"threshold_uncertainty_score":0.6283786,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03295071789971338,"score_gpt":0.346888564715604,"score_spread":0.3139378468158906,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}