{"id":"W2128708356","doi":"10.1177/1740774511424421","title":"What information should a sponsor of a randomized trial receive during its conduct?","year":2011,"lang":"en","type":"article","venue":"Clinical Trials","topic":"Ethics in Clinical Research","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hamilton Health Sciences; McMaster University; Population Health Research Institute","funders":"Canadian Institutes of Health Research","keywords":"Randomized controlled trial; Steering committee; Confidentiality; Independence (probability theory); Test (biology); Medicine; Psychology; Computer security; Computer science; Engineering","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaresearch","research_integrity","insufficient_payload"],"consensus_categories":["metaresearch"],"category_scores_codex":[0.178821,0.0002077594,0.004266153,0.0002323804,0.00005957204,0.00006182311,0.000353084,0.001220699,0.00218636],"category_scores_gemma":[0.7967731,0.0001406329,0.001872399,0.0002984715,0.0009069319,0.0007540967,0.0001945085,0.002338613,0.0003771709],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004040912,"about_ca_system_score_gemma":0.000873703,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001712879,"about_ca_topic_score_gemma":0.000004365847,"domain_scores_codex":[0.9775736,0.009878933,0.01001612,0.0004853299,0.001599913,0.0004460413],"domain_scores_gemma":[0.4271622,0.5586178,0.005985125,0.002407869,0.004461105,0.001365906],"domain_codex":null,"domain_gemma":"methods","domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9893908,0.0005388405,0.0000784182,0.0002873313,0.0005207585,0.00001268893,0.000607249,1.685981e-7,0.0002922438,0.004842705,0.0001985383,0.003230287],"study_design_scores_gemma":[0.9675829,0.001702187,0.0003782805,0.0009136742,0.0005992293,0.000005826511,0.0004014082,0.00003355041,0.007929686,0.01966019,0.0006400942,0.0001529445],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9747977,0.0004231506,0.000109538,0.00367834,0.005189162,0.008125868,0.00002344757,0.00008766674,0.007565178],"genre_scores_gemma":[0.9704261,0.01873923,0.003117991,0.001696991,0.002060496,0.0004018558,0.00002976467,0.00004007117,0.003487511],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6179521,"threshold_uncertainty_score":0.999963,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.9210380374057239,"score_gpt":0.6905986270686747,"score_spread":0.2304394103370492,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}