{"id":"W2128780965","doi":"10.1128/jvi.79.3.1803-1812.2005","title":"Mutation of the SP1 Sequence Impairs both Multimerization and Membrane-Binding Activities of Human Immunodeficiency Virus Type 1 Gag","year":2005,"lang":"en","type":"article","venue":"Journal of Virology","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":51,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Jewish General Hospital","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research","keywords":"Group-specific antigen; Capsid; Biology; Mutation; Mutant; Recombinant DNA; Molecular biology; Wild type; Peptide sequence; Virus; Raft; Cell biology; Virology; Biochemistry; Gene; Chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002152618,0.0004663826,0.0002437359,0.0001537067,0.0001594615,0.0003000551,0.0002904208,0.000394923,0.001057353],"category_scores_gemma":[0.000237849,0.0002269332,0.0002889101,0.0001083915,0.0003147355,0.0002424537,0.0002760384,0.0006104821,0.0004705018],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002489499,"about_ca_system_score_gemma":0.000200857,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005947055,"about_ca_topic_score_gemma":0.0003986267,"domain_scores_codex":[0.999772,0.00006553913,0.00003719479,0.00003064787,0.00005758688,0.00003706285],"domain_scores_gemma":[0.9997556,0.00006615123,0.00006147964,0.00003040052,0.00001412778,0.00007219712],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000105523,0.00005075214,0.0001427663,0.00001504556,0.000005586893,0.00006665635,0.00001191581,0.00009578579,0.9988714,0.00007552506,0.00001244256,0.0005465744],"study_design_scores_gemma":[0.00002995969,0.0006571273,0.003321863,0.000006910977,0.00001639538,0.0007235674,0.00002496071,0.002354147,0.9920828,0.00007558971,0.0006992383,0.000007400678],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9991271,0.0001645087,0.0004023073,0.00002050645,0.000006511305,0.000006610274,0.00005850955,0.00001658791,0.000197382],"genre_scores_gemma":[0.9982054,0.0001970366,0.0008471177,0.00001618186,0.000005596644,0.000009177425,0.000131514,0.00001301786,0.0005750005],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001057353,"threshold_uncertainty_score":0.003537238,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0215073228166985,"score_gpt":0.2977539044980213,"score_spread":0.2762465816813228,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}