{"id":"W2128782957","doi":"10.1111/j.1467-8624.2009.01381.x","title":"Epigenetics and the Biological Definition of Gene × Environment Interactions","year":2010,"lang":"en","type":"review","venue":"Child Development","topic":"Birth, Development, and Health","field":"Medicine","cited_by":1218,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Epigenetics; Phenotype; Phenotypic plasticity; Epigenesis; Biology; Gene; DNA methylation; Genetic Fitness; Psychology; Genetics; Gene expression; Evolutionary biology; Computational biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004829849,0.0008994049,0.001257264,0.002013186,0.0003509357,0.001142927,0.0009120452,0.001246865,0.00214257],"category_scores_gemma":[0.0007247633,0.0002148847,0.0003246856,0.002313011,0.002446149,0.001733369,0.000853584,0.001813205,0.0009726463],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001163546,"about_ca_system_score_gemma":0.001345674,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00160105,"about_ca_topic_score_gemma":0.002092247,"domain_scores_codex":[0.9997618,0.00008216743,0.0000253202,0.00004273031,0.00007359957,0.00001446192],"domain_scores_gemma":[0.9997113,0.0001770128,0.00003384042,0.000015144,0.00004512549,0.00001745967],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.00004794015,0.00005187236,0.0004349715,0.01025,0.0001110262,0.000544981,0.0006131446,0.0008788978,0.005298918,0.09263595,0.02781347,0.8613188],"study_design_scores_gemma":[0.000007404405,0.00003485761,0.001454447,0.002252613,0.00003548401,0.001650317,0.0002830107,0.0001193163,0.0006955895,0.02617702,0.9672638,0.00002623388],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001952566,0.9948936,0.0007315867,0.0007101725,0.0004297289,0.000004936922,0.00001641243,0.000008307125,0.003010058],"genre_scores_gemma":[0.00216874,0.9951474,0.0006645938,0.0003588119,0.0004110395,0.00001155018,0.00002144776,0.000002264434,0.001214145],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00214257,"threshold_uncertainty_score":0.008442104,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08929058009482588,"score_gpt":0.3232196714518278,"score_spread":0.2339290913570019,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}