{"id":"W2128782957","doi":"10.1111/j.1467-8624.2009.01381.x","title":"Epigenetics and the Biological Definition of Gene × Environment Interactions","year":2010,"lang":"en","type":"review","venue":"Child Development","topic":"Birth, Development, and Health","field":"Medicine","cited_by":1218,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Epigenetics; Phenotype; Phenotypic plasticity; Epigenesis; Biology; Gene; DNA methylation; Genetic Fitness; Psychology; Genetics; Gene expression; Evolutionary biology; Computational biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08929058009482588,"score_gpt":0.3232196714518278,"score_spread":0.2339290913570019,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."},"direct_labels":[],"classifier":{"requested":true,"available":true,"version":"metacan-v1-d91a1de5be90","frame_rows_covered":4299418,"decision_targets":["metaresearch","metaepi_narrow","metaepi_broad","bibliometrics","sts","scholarly_communication","open_science","research_integrity","randomized_trial","nonrandomized_trial","observational","systematic_review","meta_analysis","case_report","qualitative","simulation_or_modeling","bench_or_experimental","theoretical_or_conceptual","not_applicable"],"score_encoding":"uint16_le_65535","score_resolution":0.000015259021896696422,"interpretation":"Scores imitate each teacher on the enriched screening sample; they are not calibrated prevalence probabilities for the full frame.","warning":null},"prediction":{"classifier_version":"metacan-v1-d91a1de5be90","candidate_union":["theoretical_or_conceptual","not_applicable"],"consensus_intersection":["theoretical_or_conceptual"],"score_encoding":"uint16_le_65535","score_resolution":0.000015259021896696422,"scores":{"codex":{"metaresearch":0.0009918364232852674,"metaepi_narrow":0.00010681315327687495,"metaepi_broad":0.00022888532845044633,"bibliometrics":0.00044251163500419623,"sts":0.0009155413138017853,"scholarly_communication":0,"open_science":0.000045777065690089265,"research_integrity":0.0011291676203555353,"randomized_trial":0,"nonrandomized_trial":0.000030518043793392844,"observational":0.0012207217517357137,"systematic_review":0.004486152437628748,"meta_analysis":0.00032043945983062486,"case_report":0.00015259021896696422,"qualitative":0.00022888532845044633,"simulation_or_modeling":0.000030518043793392844,"bench_or_experimental":0.001159685664148928,"theoretical_or_conceptual":0.02844281681544213,"not_applicable":0.0011291676203555353,"design_other":0.994323643854429},"gemma":{"metaresearch":0.0003662165255207141,"metaepi_narrow":0.00006103608758678569,"metaepi_broad":0.000579842832074464,"bibliometrics":0.00025940337224383917,"sts":0.00024414435034714275,"scholarly_communication":0,"open_science":0.00015259021896696422,"research_integrity":0.0024414435034714275,"randomized_trial":0,"nonrandomized_trial":0.000015259021896696422,"observational":0.031143663691157397,"systematic_review":0.026626993209735255,"meta_analysis":0.00015259021896696422,"case_report":0.00010681315327687495,"qualitative":0.00007629510948348211,"simulation_or_modeling":0.000015259021896696422,"bench_or_experimental":0.0008087281605249104,"theoretical_or_conceptual":0.03782711528191043,"not_applicable":0.5394064240482185}},"interpretation":"Scores imitate each teacher on the enriched screening sample; they are not calibrated prevalence probabilities for the full frame."}}