{"id":"W2128802756","doi":"10.1139/o02-158","title":"Increased reactive oxygen species production with antisense oligonucleotides directed against uncoupling protein 2 in murine endothelial cells","year":2002,"lang":"en","type":"article","venue":"Biochemistry and Cell Biology","topic":"Adipose Tissue and Metabolism","field":"Medicine","cited_by":125,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Reactive oxygen species; Uncoupling protein; Superoxide; Oxidative stress; Biology; Mitochondrial ROS; Intracellular; Mitochondrion; Oligonucleotide; Biochemistry; Cell biology; Oxidative phosphorylation; Molecular biology; Enzyme; Gene; Adipose tissue; Brown adipose tissue","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002965703,0.0005334337,0.0003243292,0.000206055,0.0001273286,0.0003541309,0.0001893542,0.0003777386,0.0008974762],"category_scores_gemma":[0.0002057428,0.0002595415,0.0002660955,0.000138777,0.0002393963,0.0002004165,0.000130933,0.000811992,0.0002516672],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002306472,"about_ca_system_score_gemma":0.000162617,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004700607,"about_ca_topic_score_gemma":0.0006285614,"domain_scores_codex":[0.9996979,0.00007630341,0.00003972043,0.00006554002,0.00005851144,0.00006208922],"domain_scores_gemma":[0.9997736,0.00004494134,0.00006847432,0.00003858052,0.00003194236,0.0000424563],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006771628,0.00002377106,0.00002638627,0.00001314276,0.000003417818,0.00001212307,0.000006990404,0.00003126945,0.9994924,0.00003966313,0.00001335542,0.0002697126],"study_design_scores_gemma":[0.0000347066,0.0006417697,0.0005839553,0.000003287947,0.00001770399,0.00005302127,0.000007653145,0.0003878609,0.9974482,0.00002191991,0.0007969678,0.000002932963],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9925735,0.001355881,0.004462988,0.0001479725,0.000124852,0.00004278358,0.0002410832,0.0001256296,0.0009253146],"genre_scores_gemma":[0.9880233,0.001424808,0.007023158,0.0001594515,0.00005301585,0.0001252844,0.0006082377,0.00003976889,0.002543006],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008974762,"threshold_uncertainty_score":0.003002346,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0109027231800401,"score_gpt":0.2088345600024116,"score_spread":0.1979318368223715,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}