{"id":"W2128814992","doi":"10.1083/jcb.201111136","title":"T granules in human platelets function in TLR9 organization and signaling","year":2012,"lang":"en","type":"article","venue":"The Journal of Cell Biology","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":192,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Michael's Hospital","funders":"National Heart, Lung, and Blood Institute","keywords":"TLR9; Cell biology; Biology; Toll-Like Receptor 9; Platelet; Receptor; Intracellular; Innate immune system; Compartment (ship); Inflammation; Platelet activation; Signal transduction; Immune system; Immunology; Gene; Biochemistry; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008214595,0.0001281605,0.00009318715,0.0001783174,0.0001068244,0.0003595748,0.00007258092,0.000222484,0.0006776265],"category_scores_gemma":[0.0001279857,0.00008322544,0.000130109,0.0001048079,0.0001197098,0.0001935739,0.0001747089,0.0001954478,0.0002318778],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001289426,"about_ca_system_score_gemma":0.00006737049,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001537076,"about_ca_topic_score_gemma":0.0001276682,"domain_scores_codex":[0.9999266,0.00001797854,0.000006913323,0.00002002169,0.00001333814,0.00001512548],"domain_scores_gemma":[0.9999502,0.000008108162,0.00002008039,0.000006617916,0.000005540455,0.000009550306],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003081845,0.000007939972,0.001252675,0.00002304622,0.000003820267,0.0002717846,0.00004960458,0.00003059453,0.9959059,0.0001277173,0.00002960305,0.00198911],"study_design_scores_gemma":[0.00005117678,0.000484968,0.04402254,0.0000206097,0.00003529193,0.003133954,0.0002320107,0.001097818,0.9468114,0.0003188651,0.003781857,0.000009613321],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954576,0.001462958,0.002183702,0.00005872046,0.000008890593,0.00001451271,0.000105968,0.00002638907,0.0006811529],"genre_scores_gemma":[0.9978195,0.0004487073,0.001114055,0.00002049642,0.000009765457,0.00001247407,0.0001346049,0.000004032783,0.0004364125],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006776265,"threshold_uncertainty_score":0.002266824,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008072085934878754,"score_gpt":0.2158396773271026,"score_spread":0.2077675913922239,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}