{"id":"W2128814992","doi":"10.1083/jcb.201111136","title":"T granules in human platelets function in TLR9 organization and signaling","year":2012,"lang":"en","type":"article","venue":"The Journal of Cell Biology","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":192,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Michael's Hospital","funders":"National Heart, Lung, and Blood Institute","keywords":"TLR9; Cell biology; Biology; Toll-Like Receptor 9; Platelet; Receptor; Intracellular; Innate immune system; Compartment (ship); Inflammation; Platelet activation; Signal transduction; Immune system; Immunology; Gene; Biochemistry; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009936015,0.00006072355,0.0001397949,0.0001713347,0.00006148414,0.000002825104,0.00006978811,0.0001377061,0.00009983518],"category_scores_gemma":[0.00005561163,0.00003959404,0.00001427185,0.0001108139,0.00006285515,0.0001153325,0.00002047536,0.0002242845,0.00001900538],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002222285,"about_ca_system_score_gemma":0.00001550317,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001973676,"about_ca_topic_score_gemma":0.000006628819,"domain_scores_codex":[0.9990198,0.0004785075,0.0003062563,0.00003549186,0.00001082214,0.0001491338],"domain_scores_gemma":[0.9995494,0.0001564862,0.0001941633,0.0000500938,0.00004305729,0.000006823361],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002114024,0.00004242102,0.01115577,0.000004109944,0.00001119738,6.488881e-7,0.001079323,0.00001801092,0.985849,0.000277753,0.00001596765,0.001334433],"study_design_scores_gemma":[0.001069918,0.0002398008,0.04130205,0.00001735605,0.00002071631,0.0001390234,0.0003659826,0.000001913718,0.9547625,0.0004237678,0.001597546,0.00005942474],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9953155,0.003904037,0.0002424424,0.00007003982,0.000287495,0.00005112446,2.425976e-7,0.000003144795,0.0001259641],"genre_scores_gemma":[0.9995057,0.0003405963,0.000009035582,0.00004084655,0.00004340602,3.427917e-7,0.0000105753,0.000004629147,0.00004489592],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03108646,"threshold_uncertainty_score":0.1614598,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008072085934878754,"score_gpt":0.2158396773271026,"score_spread":0.2077675913922239,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}