{"id":"W2128877207","doi":"10.1111/hiv.12141","title":"Etravirine in treatment‐experienced, <scp>HIV</scp>‐1‐infected children and adolescents: 48‐week safety, efficacy and resistance analysis of the phase <scp>II PIANO</scp> study","year":2014,"lang":"en","type":"article","venue":"HIV Medicine","topic":"HIV/AIDS drug development and treatment","field":"Medicine","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre","funders":"Janssen Pharmaceuticals; Janssen Research and Development; ViiV Healthcare","keywords":"Etravirine; Medicine; Tolerability; Efavirenz; Regimen; Viral load; Nevirapine; Internal medicine; Adverse effect; Rash; Gastroenterology; Human immunodeficiency virus (HIV); Immunology; Antiretroviral therapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00133675,0.0003827084,0.0007334677,0.0001549159,0.0001773828,0.0004717871,0.0003199604,0.0004785357,0.0009735985],"category_scores_gemma":[0.0007832208,0.0002979048,0.0006464749,0.0001920903,0.0003332543,0.0003588854,0.0001846683,0.001265005,0.0001826156],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004059099,"about_ca_system_score_gemma":0.0005895206,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008042234,"about_ca_topic_score_gemma":0.001792898,"domain_scores_codex":[0.9995715,0.0002579378,0.00002564188,0.00004655075,0.00005494788,0.00004350165],"domain_scores_gemma":[0.9992699,0.0001617782,0.0002876134,0.00004919922,0.00005809736,0.0001734538],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.4194709,0.04796287,0.267645,0.001951653,0.003554319,0.0009019218,0.001209319,0.002800795,0.06156493,0.0003606918,0.004089391,0.1884882],"study_design_scores_gemma":[0.1784801,0.4471759,0.3496511,0.0002091748,0.001388191,0.001909248,0.0003033406,0.00218999,0.01211312,0.0001268627,0.006412652,0.00004033887],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9985877,0.0006847756,0.00007159768,0.00004125904,0.000006915091,0.0001634178,0.0002130304,0.00000548048,0.0002258769],"genre_scores_gemma":[0.997647,0.0007956369,0.0004319823,0.0001279034,0.00002671607,0.000223479,0.0004419223,0.000005932227,0.0002994818],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00133675,"threshold_uncertainty_score":0.007069528,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009750343844143116,"score_gpt":0.2721351079692547,"score_spread":0.2623847641251116,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}