{"id":"W2128877207","doi":"10.1111/hiv.12141","title":"Etravirine in treatment‐experienced, <scp>HIV</scp>‐1‐infected children and adolescents: 48‐week safety, efficacy and resistance analysis of the phase <scp>II PIANO</scp> study","year":2014,"lang":"en","type":"article","venue":"HIV Medicine","topic":"HIV/AIDS drug development and treatment","field":"Medicine","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre","funders":"Janssen Pharmaceuticals; Janssen Research and Development; ViiV Healthcare","keywords":"Etravirine; Medicine; Tolerability; Efavirenz; Regimen; Viral load; Nevirapine; Internal medicine; Adverse effect; Rash; Gastroenterology; Human immunodeficiency virus (HIV); Immunology; Antiretroviral therapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005196296,0.0005165599,0.001360502,0.0006920777,0.0002246837,0.00001517927,0.0001900232,0.0001133164,0.00002510629],"category_scores_gemma":[0.001035648,0.0003164067,0.0001160767,0.001947293,0.0004677109,0.00008973011,0.0001327305,0.0002422941,0.000009855498],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001561314,"about_ca_system_score_gemma":0.00008309494,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001110451,"about_ca_topic_score_gemma":0.000575821,"domain_scores_codex":[0.9969525,0.0002576642,0.0008508166,0.0007658126,0.0006741472,0.000499072],"domain_scores_gemma":[0.9979663,0.0005072338,0.0003137229,0.0007558148,0.0001153228,0.0003415437],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0002443614,0.006038377,0.9630575,0.0000629686,0.001699572,0.00006108994,0.02160789,0.000004751772,0.001036028,0.00006001052,0.002658374,0.003469115],"study_design_scores_gemma":[0.04338547,0.001567893,0.9423047,0.0006093665,0.003356733,0.00001866232,0.002378267,0.0001441893,0.0006166828,0.00001125602,0.005525814,0.00008096413],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9935929,0.001047963,0.00007117087,0.001341266,0.00007764101,0.001692475,0.00004252794,0.00005792962,0.002076097],"genre_scores_gemma":[0.9880741,0.0006753331,0.0001582501,0.0001736258,0.000109358,0.00005548937,0.0002340271,0.00003759115,0.01048227],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04314111,"threshold_uncertainty_score":0.9999288,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009750343844143116,"score_gpt":0.2721351079692547,"score_spread":0.2623847641251116,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}