{"id":"W2128892592","doi":"10.1101/gr.652803","title":"The Genetic Core of the Universal Ancestor","year":2003,"lang":"en","type":"article","venue":"Genome Research","topic":"RNA and protein synthesis mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":293,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Biology; Gene; Phylogenetic tree; Genetics; Genome; Phylogenetics; Ribosomal RNA; Ribosome; Evolutionary biology; Horizontal gene transfer; Transfer RNA; Most recent common ancestor; Ancestor; RNA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004792716,0.0001752526,0.0005396177,0.0008219974,0.0008716438,0.001041275,0.0003820281,0.0005032435,0.001600099],"category_scores_gemma":[0.001319579,0.0002431014,0.0002522981,0.0007270669,0.001158591,0.0009575037,0.001341482,0.0009622704,0.0003273311],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000890718,"about_ca_system_score_gemma":0.001030051,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001967096,"about_ca_topic_score_gemma":0.001849654,"domain_scores_codex":[0.9995827,0.00005848557,0.00002613278,0.000143624,0.00008891962,0.000100214],"domain_scores_gemma":[0.9993806,0.0001283318,0.0001056489,0.0001347012,0.0001064817,0.0001441278],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.0007332454,0.00009714413,0.07491524,0.0005467366,0.0001546081,0.002700168,0.006990364,0.003756831,0.6053976,0.1542514,0.000989323,0.1494673],"study_design_scores_gemma":[0.0001283973,0.0007855907,0.5575305,0.0005705249,0.0004668432,0.008241817,0.003831167,0.01558913,0.08729301,0.1940714,0.1311845,0.0003069137],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9731118,0.001851857,0.01523192,0.0004141698,0.00002218136,0.00002879219,0.0002689737,0.0001293625,0.00894095],"genre_scores_gemma":[0.9893924,0.0007208083,0.007929477,0.0001691786,0.00001666696,0.00001820919,0.0004198626,0.00004800902,0.001285475],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001967096,"threshold_uncertainty_score":0.006462634,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06093309368026626,"score_gpt":0.3193561772589045,"score_spread":0.2584230835786382,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}