{"id":"W2128896236","doi":"10.1128/iai.01265-07","title":"Activation of the Cpx Envelope Stress Response Down-Regulates Expression of Several Locus of Enterocyte Effacement-Encoded Genes in Enteropathogenic <i>Escherichia coli</i>","year":2008,"lang":"en","type":"article","venue":"Infection and Immunity","topic":"Escherichia coli research studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":77,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Intimin; Biology; Pathogenicity island; Enteropathogenic Escherichia coli; Operon; Virulence; Secretion; Escherichia coli; Bacterial adhesin; Microbiology; Gene; Transcription (linguistics); Cell biology; Genetics; Enterobacteriaceae; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003034615,0.0001037022,0.0001664044,0.00005793097,0.00009762648,0.000003281985,0.0001033503,0.00007917084,0.000006617712],"category_scores_gemma":[0.0001861297,0.00007998775,0.00006274828,0.0001630964,0.0002188806,0.0000123182,0.0002401157,0.0001097906,1.30299e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001818466,"about_ca_system_score_gemma":0.0000645605,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003961358,"about_ca_topic_score_gemma":0.00008139319,"domain_scores_codex":[0.9988372,0.0005223297,0.0002673674,0.0001250508,0.0001348756,0.0001132114],"domain_scores_gemma":[0.9993712,0.00004231886,0.0001854643,0.0002415761,0.0001373703,0.00002201069],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001075276,0.0001573666,0.1501985,0.00005481971,0.00002577045,1.419828e-7,0.0003276023,0.0001758347,0.8478168,8.833816e-7,0.00001704067,0.0001499569],"study_design_scores_gemma":[0.0005168359,0.0001789459,0.3847843,0.00005276695,0.000003548982,0.000001318072,0.00006790215,0.00002594348,0.6141749,0.000002003403,0.0001503053,0.00004121925],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9991518,0.0003313002,0.0001597416,0.00002304688,0.00004847318,0.0002233933,0.00001599217,0.000003414643,0.00004286754],"genre_scores_gemma":[0.9985305,0.001268879,0.0000725183,0.00001638569,0.000009622173,0.00001775942,0.00001031993,0.000006673929,0.00006734032],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2345858,"threshold_uncertainty_score":0.3261805,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01319594758827356,"score_gpt":0.2495052947205311,"score_spread":0.2363093471322576,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}