{"id":"W2128917960","doi":"10.1002/jgm.1346","title":"Diverse genomic integration of a lentiviral vector developed for the treatment of Wiskott–Aldrich syndrome","year":2009,"lang":"en","type":"article","venue":"The Journal of Gene Medicine","topic":"Cellular Mechanics and Interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Wiskott–Aldrich syndrome; Viral vector; Virology; Vector (molecular biology); Computational biology; Biology; Genetics; Gene; Recombinant DNA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004525032,0.0005379797,0.0003387822,0.0006607815,0.0002039473,0.0004983192,0.0003205971,0.000355953,0.0008619637],"category_scores_gemma":[0.0001860323,0.0002166744,0.0002980446,0.0003497479,0.0004000997,0.0002494722,0.0002902995,0.0009561746,0.0004303023],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003554852,"about_ca_system_score_gemma":0.0003704378,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000269684,"about_ca_topic_score_gemma":0.0005036154,"domain_scores_codex":[0.9995853,0.00005794718,0.00005875641,0.00007925155,0.000168879,0.00004988252],"domain_scores_gemma":[0.9997991,0.00002306387,0.00006963459,0.00002806149,0.00002731026,0.00005296439],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000438381,0.00003528118,0.000456828,0.00004547256,0.00001406127,0.00006246231,0.00001272665,0.00007735984,0.9959952,0.0002330006,0.00005760524,0.002966255],"study_design_scores_gemma":[0.00002648677,0.0006570815,0.00469453,0.00002048446,0.00008603733,0.0009746323,0.00002051073,0.001187777,0.9869265,0.0001053627,0.005291931,0.000008669001],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9618515,0.003134573,0.03021853,0.0001655465,0.0001121804,0.0003447052,0.0009378677,0.0004573925,0.002777653],"genre_scores_gemma":[0.9746943,0.001939302,0.01849094,0.0001200915,0.00002763815,0.000140826,0.002334072,0.00009345639,0.00215947],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008619637,"threshold_uncertainty_score":0.002883613,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02734340092159986,"score_gpt":0.2846649891031665,"score_spread":0.2573215881815666,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}