{"id":"W2128932714","doi":"10.5732/cjc.010.10162","title":"Protein folding, protein homeostasis, and cancer","year":2011,"lang":"en","type":"review","venue":"Chinese Journal of Cancer","topic":"Heat shock proteins research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":43,"is_retracted":false,"has_abstract":true,"ca_institutions":"Vanier College","funders":"University of California, San Francisco","keywords":"Protein folding; Computational biology; Folding (DSP implementation); Cancer; Sequence (biology); Cancer cell; Cell biology; Biology; Chemistry; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005984238,0.0005291613,0.001396757,0.0002563322,0.00008768338,0.00005944928,0.0005826718,0.0004974089,0.0003033107],"category_scores_gemma":[0.0002670359,0.0003302711,0.0004946417,0.00026934,0.0001313402,0.00001354216,0.0002825821,0.0007592061,0.000004905642],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001330532,"about_ca_system_score_gemma":0.00189114,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001436334,"about_ca_topic_score_gemma":0.0001034593,"domain_scores_codex":[0.9977216,0.0002483829,0.0008223836,0.0004045781,0.0003709403,0.0004321331],"domain_scores_gemma":[0.9980975,0.00001178563,0.0007665234,0.0004116301,0.0003990824,0.000313493],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007519202,0.00004374293,0.00003708712,0.006558354,0.0005186634,0.00002667881,0.00002325131,3.480046e-7,0.004445755,0.000008408113,0.0006458918,0.9876166],"study_design_scores_gemma":[0.0003996043,0.0003857047,0.00001667345,0.009472072,0.0001856752,0.0001041372,0.000002766613,3.863985e-7,0.002511958,0.00003900399,0.9865209,0.0003610546],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.008863902,0.9891577,0.00002501481,0.00006302148,0.0001880897,0.001375494,0.00008694271,0.000004771736,0.0002350107],"genre_scores_gemma":[0.0007208079,0.9954281,0.000237304,0.00002372439,0.001623122,0.0005928239,0.00001174367,0.0001097387,0.001252615],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9872556,"threshold_uncertainty_score":0.9999149,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03662050494126207,"score_gpt":0.386207603129738,"score_spread":0.3495870981884759,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}