{"id":"W2129000165","doi":"10.1002/anie.201100477","title":"Fluorogenic DNAzyme Probes as Bacterial Indicators","year":2011,"lang":"en","type":"article","venue":"Angewandte Chemie International Edition","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":231,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"","keywords":"Deoxyribozyme; Fluorophore; Cleave; DNA; Nucleic acid; RNA; Nucleotide; Fluorescence; Computational biology; Bacteria; Chemistry; Biochemistry; Biology; Genetics; Gene; Physics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000906498,0.0001342126,0.00009259342,0.00008968722,0.00005214451,0.00002074271,0.0001889397,0.0001507375,0.0001507442],"category_scores_gemma":[0.00007590143,0.0001239971,0.0001126163,0.00008290241,0.00008428607,0.00001405812,0.00007495321,0.00007097973,0.00002077019],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002892149,"about_ca_system_score_gemma":0.00003488818,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001885673,"about_ca_topic_score_gemma":0.000009639212,"domain_scores_codex":[0.999197,0.00001401084,0.0001819303,0.0002914217,0.0001737364,0.000141881],"domain_scores_gemma":[0.9995325,0.000004079432,0.0001166202,0.0001733302,0.0001140301,0.00005941893],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001063375,0.00008135758,0.0004390227,0.000003031485,0.00009632776,0.000004460102,0.00003447526,6.796048e-8,0.9918081,0.0001214111,0.005728671,0.001576705],"study_design_scores_gemma":[0.0002059997,0.0001076536,0.0005019428,0.00001300028,0.00002290475,0.00002706174,0.00002799309,0.000001198856,0.9607127,0.0005878059,0.03763863,0.0001531455],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9757022,0.00007299765,0.002428116,0.0002061277,0.0008183623,0.0001392209,0.00008445132,0.0001003118,0.02044823],"genre_scores_gemma":[0.9940125,0.0001521522,0.002032798,0.0002592012,0.001467162,0.00002326137,0.001325092,0.00001658478,0.0007112402],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03190996,"threshold_uncertainty_score":0.5056454,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01247727509635173,"score_gpt":0.2586580980256757,"score_spread":0.2461808229293239,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}