{"id":"W2129028798","doi":"10.1128/iai.00025-15","title":"The Serine Protease Autotransporter Pic Modulates Citrobacter rodentium Pathogenesis and Its Innate Recognition by the Host","year":2015,"lang":"en","type":"article","venue":"Infection and Immunity","topic":"Escherichia coli research studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; University of British Columbia; Child and Family Research Institute","funders":"Canadian Institutes of Health Research; University of British Columbia","keywords":"Citrobacter rodentium; Biology; Microbiology; Shigella flexneri; Enteroaggregative Escherichia coli; Mutant; Pathogenic Escherichia coli; Pathogen; Virulence; Innate immune system; TLR2; Enterobacteriaceae; Escherichia coli; Immunology; Immune system; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001235327,0.000294228,0.0001904927,0.0001534658,0.00008559941,0.0002828044,0.0001928405,0.0002575652,0.0004307037],"category_scores_gemma":[0.0001282555,0.0001203881,0.0001298532,0.00009589982,0.0002321773,0.000177925,0.0002042096,0.0004119294,0.000113209],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002537908,"about_ca_system_score_gemma":0.0001790445,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000531327,"about_ca_topic_score_gemma":0.0005486393,"domain_scores_codex":[0.9998104,0.00003711489,0.00001555813,0.0000363693,0.00003882692,0.000061708],"domain_scores_gemma":[0.9998752,0.000007845575,0.00004622522,0.00001051198,0.00001503056,0.00004513452],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001583739,0.00002679215,0.0006221858,0.00002706346,0.000002999344,0.00005645284,0.00001301634,0.00004656553,0.997976,0.00004375194,0.00002949133,0.0009973901],"study_design_scores_gemma":[0.00004871395,0.001073974,0.07286066,0.00002932034,0.00005115398,0.0008849293,0.0001901493,0.003654424,0.9184188,0.0001502225,0.002616507,0.00002115891],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971819,0.001452575,0.0004610398,0.00008743097,0.00001082988,0.000008077637,0.00007928888,0.00003633414,0.0006825388],"genre_scores_gemma":[0.9987471,0.0003759474,0.0003758628,0.00003691778,0.000004281616,0.000007384605,0.00006589539,0.000005734005,0.0003808548],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000531327,"threshold_uncertainty_score":0.001841426,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02241754374212346,"score_gpt":0.2579905809899025,"score_spread":0.2355730372477791,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}