{"id":"W2129105278","doi":"10.1002/hep.28013","title":"A targeted functional RNA interference screen uncovers glypican 5 as an entry factor for hepatitis B and D viruses","year":2015,"lang":"en","type":"article","venue":"Hepatology","topic":"Hepatitis B Virus Studies","field":"Medicine","cited_by":169,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Canadian Institutes of Health Research; Université de Strasbourg; Institut National de la Santé et de la Recherche Médicale; Agence Nationale de Recherches sur le Sida et les Hépatites Virales; Agence Nationale de la Recherche; Interreg; National Institute of Allergy and Infectious Diseases; Universität Heidelberg; European Commission; Broad Institute","keywords":"Glypican 3; Virology; RNA interference; RNA; Hepatitis virus; Biology; Computational biology; Medicine; Hepatitis; Genetics; Gene; Hepatocellular carcinoma","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002138614,0.0004427364,0.0002950716,0.000346276,0.0002250571,0.0003793703,0.0003462592,0.0003536718,0.001067107],"category_scores_gemma":[0.0001783034,0.0001376754,0.0003349843,0.0001603003,0.0002631776,0.0001122741,0.0002310434,0.0003851046,0.0004114777],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004006002,"about_ca_system_score_gemma":0.000257247,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007627949,"about_ca_topic_score_gemma":0.001417394,"domain_scores_codex":[0.9998176,0.00002861488,0.00001904276,0.00003571486,0.00007527982,0.00002373393],"domain_scores_gemma":[0.9998648,0.00005321759,0.00003419047,0.00001207898,0.00001217514,0.00002352141],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004551856,0.00001357029,0.0001368476,0.00001550265,0.000004864416,0.00006080389,0.000005284232,0.00007790804,0.9988338,0.0000602751,0.00002643278,0.0007191945],"study_design_scores_gemma":[0.0000174224,0.0002803578,0.002084739,0.00000466865,0.00004988116,0.0003893931,0.00002026268,0.002280312,0.9925554,0.00004650349,0.002263927,0.000007130841],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9805186,0.001382674,0.0136585,0.0002051527,0.00005082682,0.0001081609,0.0009058092,0.0002226697,0.002947537],"genre_scores_gemma":[0.983456,0.0007984885,0.01210847,0.0001775562,0.0000114811,0.00004615787,0.00138403,0.00005398002,0.001963838],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001067107,"threshold_uncertainty_score":0.003569841,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07868191352617628,"score_gpt":0.3214873193861139,"score_spread":0.2428054058599377,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}