{"id":"W2129105278","doi":"10.1002/hep.28013","title":"A targeted functional RNA interference screen uncovers glypican 5 as an entry factor for hepatitis B and D viruses","year":2015,"lang":"en","type":"article","venue":"Hepatology","topic":"Hepatitis B Virus Studies","field":"Medicine","cited_by":169,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Canadian Institutes of Health Research; Université de Strasbourg; Institut National de la Santé et de la Recherche Médicale; Agence Nationale de Recherches sur le Sida et les Hépatites Virales; Agence Nationale de la Recherche; Interreg; National Institute of Allergy and Infectious Diseases; Universität Heidelberg; European Commission; Broad Institute","keywords":"Glypican 3; Virology; RNA interference; RNA; Hepatitis virus; Biology; Computational biology; Medicine; Hepatitis; Genetics; Gene; Hepatocellular carcinoma","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000100637,0.0002059182,0.0004683434,0.0001224971,0.00009828124,0.00001712486,0.00006221797,0.0001511518,0.0002927015],"category_scores_gemma":[0.0007824171,0.0001860913,0.00005806523,0.00009997185,0.00024789,0.0001471194,0.00008729528,0.0001528293,0.00006950063],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00013214,"about_ca_system_score_gemma":0.0003284208,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.008527038,"about_ca_topic_score_gemma":0.01343788,"domain_scores_codex":[0.9987047,0.00008185945,0.0002755196,0.0003992769,0.0001834214,0.0003552125],"domain_scores_gemma":[0.9989017,0.0001674467,0.00008762915,0.0002263069,0.0002707364,0.0003461984],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0009333515,0.00009164442,0.9843094,0.00003339488,0.0001505394,0.00006280547,0.0006573008,2.848324e-7,0.0008073194,0.001335069,0.007417676,0.004201236],"study_design_scores_gemma":[0.0106725,0.009139028,0.8160985,0.0001509348,0.0003918014,0.0008696467,0.0006839422,0.002869532,0.01190525,0.005336847,0.1409264,0.0009556621],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.994491,0.0004504609,0.001435011,0.0008154076,0.000469828,0.0004448397,0.0002590119,0.0001135793,0.001520795],"genre_scores_gemma":[0.994959,0.0001883965,0.001392915,0.00277727,0.0001837845,0.00008770798,0.00007850449,0.00002798061,0.0003044215],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1682109,"threshold_uncertainty_score":0.9980752,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07868191352617628,"score_gpt":0.3214873193861139,"score_spread":0.2428054058599377,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}