{"id":"W2129113026","doi":"10.1093/infdis/jiq102","title":"The Y238X Stop Codon Polymorphism in the Human β-Glucan Receptor Dectin-1 and Susceptibility to Invasive Aspergillosis","year":2011,"lang":"en","type":"article","venue":"The Journal of Infectious Diseases","topic":"Antifungal resistance and susceptibility","field":"Medicine","cited_by":116,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"Radboud Universitair Medisch Centrum; Leids Universitair Medisch Centrum","keywords":"Biology; Aspergillosis; Immunology; Hematopoietic stem cell transplantation; Loss of heterozygosity; Genotype; Immune system; Allele; Aspergillus; Odds ratio; Myeloid; Stem cell; Internal medicine; Genetics; Medicine; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001691291,0.000182519,0.0003300814,0.00009592946,0.000553038,0.00004403925,0.0003057418,0.00005554839,0.0001493405],"category_scores_gemma":[0.00161722,0.00008126706,0.0001803804,0.0003043983,0.0003997041,0.000118192,0.00006634902,0.0004168707,0.00001141698],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000161672,"about_ca_system_score_gemma":0.0002053325,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007766006,"about_ca_topic_score_gemma":0.004740551,"domain_scores_codex":[0.9980388,0.0005870843,0.0005089542,0.0001640653,0.0004158754,0.0002852235],"domain_scores_gemma":[0.9977962,0.000932624,0.000270298,0.0005071817,0.0002741472,0.0002195728],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001063344,0.0004500062,0.9844396,0.00003782858,0.00009590023,0.00002410744,0.004842617,0.000001358175,0.004998934,0.0002306375,0.002000568,0.001815135],"study_design_scores_gemma":[0.0008041438,0.001240874,0.9890166,0.000128772,0.0002537897,0.0001185944,0.005468158,7.096349e-7,0.001221738,0.001357823,0.0002868639,0.0001019274],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9948852,0.001764444,0.00001703469,0.001361468,0.0001635787,0.0004680471,0.0000102282,0.00001527037,0.001314694],"genre_scores_gemma":[0.997779,0.0008918359,0.00001145487,0.0009718668,0.000198752,0.000008595077,0.000001070534,0.00001539261,0.0001221074],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004577044,"threshold_uncertainty_score":0.4253577,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02447030561687826,"score_gpt":0.2778192109682336,"score_spread":0.2533489053513554,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}