{"id":"W2129113026","doi":"10.1093/infdis/jiq102","title":"The Y238X Stop Codon Polymorphism in the Human β-Glucan Receptor Dectin-1 and Susceptibility to Invasive Aspergillosis","year":2011,"lang":"en","type":"article","venue":"The Journal of Infectious Diseases","topic":"Antifungal resistance and susceptibility","field":"Medicine","cited_by":116,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"Radboud Universitair Medisch Centrum; Leids Universitair Medisch Centrum","keywords":"Biology; Aspergillosis; Immunology; Hematopoietic stem cell transplantation; Loss of heterozygosity; Genotype; Immune system; Allele; Aspergillus; Odds ratio; Myeloid; Stem cell; Internal medicine; Genetics; Medicine; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002167872,0.000320455,0.0002437661,0.00031436,0.0001658423,0.0001948756,0.0001377042,0.0003511864,0.001790781],"category_scores_gemma":[0.0007237942,0.0001101345,0.000255415,0.0002195011,0.0001702202,0.00009277194,0.0001477991,0.0002625465,0.0002141706],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009285275,"about_ca_system_score_gemma":0.00008329222,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004645831,"about_ca_topic_score_gemma":0.0002840943,"domain_scores_codex":[0.9998469,0.00004614133,0.00001965747,0.0000381751,0.00002511026,0.00002390258],"domain_scores_gemma":[0.9994074,0.0001945138,0.0002288216,0.00002962232,0.00003170781,0.0001078893],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00269333,0.0001854503,0.9481772,0.00003973604,0.0002271422,0.002834145,0.000114402,0.0003901286,0.04021018,0.00008048447,0.0001447159,0.004903135],"study_design_scores_gemma":[0.0001156936,0.001317825,0.9771617,0.00001311726,0.0001815593,0.01315449,0.0001120236,0.001242799,0.006158157,0.0001399873,0.0003897528,0.00001276426],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9997444,0.00007976335,0.0000713437,0.00001257434,0.000002885859,0.000002065613,0.00001925914,0.000001642691,0.00006618943],"genre_scores_gemma":[0.9998111,0.00002360622,0.00005796204,0.000007035444,0.000005542031,0.000001675341,0.00002847765,0.000001062512,0.00006361467],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001790781,"threshold_uncertainty_score":0.005990803,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02447030561687826,"score_gpt":0.2778192109682336,"score_spread":0.2533489053513554,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}