{"id":"W2129282255","doi":"10.1091/mbc.e08-02-0161","title":"A Novel Juxtamembrane Domain in Tumor Necrosis Factor Receptor Superfamily Molecules Activates Rac1 and Controls Neurite Growth","year":2008,"lang":"en","type":"article","venue":"Molecular Biology of the Cell","topic":"Phagocytosis and Immune Regulation","field":"Immunology and Microbiology","cited_by":45,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research; Parkinson Society Canada","keywords":"Biology; RAC1; Neurite; Cell biology; Cancer research; Receptor; SUPERFAMILY; Tumor necrosis factor alpha; Signal transduction; Genetics; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008388926,0.0001760139,0.0001105854,0.0001131731,0.0002221459,0.0002614776,0.0001867959,0.0002555597,0.0005243454],"category_scores_gemma":[0.0001128021,0.00009826492,0.0001323849,0.0000823121,0.0002617472,0.000252236,0.0002356895,0.0003975705,0.0003642996],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003795327,"about_ca_system_score_gemma":0.0001972819,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001572409,"about_ca_topic_score_gemma":0.000268284,"domain_scores_codex":[0.9999343,0.000008839063,0.000004741038,0.00001749856,0.00002011663,0.00001440435],"domain_scores_gemma":[0.9999349,0.00001049857,0.00001863941,0.000008732551,0.000008237622,0.00001900568],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006126682,0.00001053978,0.0001537597,0.00001448999,0.000001033997,0.0001018196,0.000008230348,0.00003661567,0.9979626,0.0004308261,0.0000198252,0.001198952],"study_design_scores_gemma":[0.00003373985,0.0002569769,0.006719191,0.000007515981,0.00001333554,0.002575365,0.00003773631,0.001990447,0.9806219,0.0003679003,0.007367244,0.000008582759],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9921615,0.001736762,0.004762903,0.0001040343,0.00002042537,0.00001201254,0.00006867809,0.00004229472,0.001091425],"genre_scores_gemma":[0.9939459,0.0005924972,0.00374297,0.00004237976,0.00001225641,0.00001351299,0.0001856588,0.000007772017,0.001457196],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005243454,"threshold_uncertainty_score":0.002753735,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008273525026789234,"score_gpt":0.2035204159667703,"score_spread":0.1952468909399811,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}