{"id":"W2129535039","doi":"10.1016/j.jmb.2011.08.047","title":"Iron-Coordinating Tyrosine Is a Key Determinant of NEAT Domain Heme Transfer","year":2011,"lang":"en","type":"article","venue":"Journal of Molecular Biology","topic":"Hemoglobin structure and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":54,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; University of Saskatchewan; National Research Council Canada; Indiana State Department of Health","keywords":"Heme; Chemistry; Hemoglobin; Protoporphyrin IX; Hemeprotein; Biophysics; Stereochemistry; Biochemistry; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000150983,0.0001803773,0.0001911375,0.00006357503,0.0001324148,0.0001988452,0.0002123285,0.0001872342,0.0006532706],"category_scores_gemma":[0.0002819932,0.0001030715,0.0001591688,0.00008129598,0.0001742067,0.0002109906,0.0001577192,0.0003226634,0.0002277089],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002532075,"about_ca_system_score_gemma":0.0001803508,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007689793,"about_ca_topic_score_gemma":0.0006230198,"domain_scores_codex":[0.9998901,0.00001340063,0.000007313059,0.00003224747,0.00003644119,0.00002055088],"domain_scores_gemma":[0.9998636,0.00002974789,0.00004156111,0.0000114456,0.00002467857,0.00002892239],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001196681,0.0000247588,0.001661944,0.00003522978,0.000003495804,0.0000739957,0.00002660245,0.0001071507,0.9966692,0.0001399061,0.00003129472,0.00110689],"study_design_scores_gemma":[0.00001164857,0.0001362147,0.01592175,0.000005708944,0.000007548105,0.0003706575,0.00006045384,0.003227204,0.9791988,0.00008056135,0.000971577,0.000007839639],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9981585,0.0001506977,0.001247,0.00002050945,0.000006599144,0.00000735754,0.00004276631,0.00001515884,0.0003514622],"genre_scores_gemma":[0.9981112,0.00007706562,0.001126039,0.00001182504,0.000001409525,0.000004864607,0.0001103406,0.00000615675,0.000551055],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007689793,"threshold_uncertainty_score":0.002185404,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01012890867282644,"score_gpt":0.2424193675477879,"score_spread":0.2322904588749614,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}