{"id":"W2129559462","doi":"10.1128/aac.02150-13","title":"Novel Composite Efficacy Measure To Demonstrate the Rationale and Efficacy of Combination Antiviral–Anti-Inflammatory Treatment for Recurrent Herpes Simplex Labialis","year":2013,"lang":"en","type":"review","venue":"Antimicrobial Agents and Chemotherapy","topic":"Herpesvirus Infections and Treatments","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Valeant Pharmaceuticals International; Novartis Pharmaceuticals Corporation; GlaxoSmithKline","keywords":"Herpes simplex virus; Medicine; Lesion; Herpes Labialis; Target lesion; Internal medicine; Clinical trial; Randomized controlled trial; Gastroenterology; Immunology; Dermatology; Surgery; Virus","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002462127,0.001116734,0.00298816,0.002937554,0.0001735193,0.0008779386,0.001308411,0.001113121,0.003956324],"category_scores_gemma":[0.002540086,0.0003305924,0.001489803,0.001760625,0.0003960297,0.001017554,0.0003884623,0.00124413,0.0006387636],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007127883,"about_ca_system_score_gemma":0.000860457,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007156518,"about_ca_topic_score_gemma":0.001782341,"domain_scores_codex":[0.9987898,0.0004593346,0.0002399033,0.0001094471,0.0003674098,0.00003400609],"domain_scores_gemma":[0.9988607,0.00069147,0.0002389283,0.00002086112,0.000164634,0.00002331816],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0006586126,0.0003328804,0.0005859288,0.172888,0.002046379,0.000201427,0.00012279,0.0007464187,0.004006335,0.006176022,0.007637114,0.8045981],"study_design_scores_gemma":[0.001131756,0.003769142,0.01554917,0.08697141,0.01138627,0.004164849,0.000495012,0.002140718,0.008057956,0.007100177,0.8590388,0.0001947131],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0007384357,0.9969563,0.0004269674,0.0001637402,0.0001041908,0.0001227557,0.00008133001,0.000007752682,0.001398438],"genre_scores_gemma":[0.01742314,0.9769523,0.003387558,0.0004401751,0.0001580342,0.0003577904,0.0001539188,0.000005934367,0.001121076],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003956324,"threshold_uncertainty_score":0.01323521,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0628517817043064,"score_gpt":0.3422347297430923,"score_spread":0.2793829480387859,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}