{"id":"W2129761500","doi":"10.1615/critrevneurobiol.v18.i1-2.80","title":"Hippocampal Long-Term Synaptic Plasticity and Signal Amplification of NMDA Receptors","year":2006,"lang":"en","type":"review","venue":"Critical Reviews in Neurobiology","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":173,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canada Research Chairs; University of Toronto","funders":"","keywords":"Long-term potentiation; Long-term depression; Synaptic plasticity; Neuroscience; LTP induction; NMDA receptor; Excitatory postsynaptic potential; Metaplasticity; Postsynaptic potential; Biology; Dendritic spine; Nonsynaptic plasticity; Chemistry; Neurotransmission; AMPA receptor; Cell biology; Receptor; Hippocampal formation; Inhibitory postsynaptic potential; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001593115,0.0004962161,0.0005137625,0.0003069765,0.0001072057,0.0003703073,0.0003401201,0.000344782,0.0009101511],"category_scores_gemma":[0.0001414635,0.0001009871,0.0002762875,0.0003720467,0.00027765,0.000544221,0.0002829965,0.0004736506,0.0005353009],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003543132,"about_ca_system_score_gemma":0.00021508,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000428529,"about_ca_topic_score_gemma":0.0004485843,"domain_scores_codex":[0.9998838,0.00001222431,0.00001499479,0.0000282864,0.00003827052,0.00002243795],"domain_scores_gemma":[0.9999559,0.000009099219,0.00001315231,0.000001831343,0.000014281,0.000005706263],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000360613,0.00006089048,0.001585552,0.01229965,0.0001488366,0.002144553,0.0002632628,0.001223838,0.3560643,0.01083236,0.005463331,0.6095528],"study_design_scores_gemma":[0.00006950489,0.001382747,0.04270215,0.001406562,0.0004031103,0.01119711,0.0002632887,0.001449529,0.2500186,0.01208335,0.6789302,0.00009384195],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.02733428,0.9613066,0.003792996,0.0003874586,0.000373326,0.00002582906,0.0001269554,0.00009761581,0.006554944],"genre_scores_gemma":[0.1046143,0.8882756,0.001519473,0.0003095086,0.0004390308,0.00003247031,0.0002063412,0.000009732866,0.004593626],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.0009101511,"threshold_uncertainty_score":0.003044784,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1693887471837968,"score_gpt":0.445957192267937,"score_spread":0.2765684450841401,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}