{"id":"W2129806278","doi":"10.4049/jimmunol.177.6.3728","title":"A New Memory CD27−IgG+ B Cell Population in Peripheral Blood Expressing VH Genes with Low Frequency of Somatic Mutation","year":2006,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":298,"is_retracted":false,"has_abstract":true,"ca_institutions":"Héma-Québec","funders":"","keywords":"Somatic hypermutation; Germinal center; Biology; Immunoglobulin D; B cell; Antibody; Naive B cell; Antigen; Population; B-1 cell; Molecular biology; Gene; Memory B cell; Somatic cell; Immunology; Genetics; T cell; Immune system; Antigen-presenting cell; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009925547,0.0001639374,0.000245783,0.0006741337,0.0002040346,0.0005122318,0.0002388669,0.0002484214,0.003210021],"category_scores_gemma":[0.0002128774,0.0001228166,0.0001068365,0.0003512184,0.0001548109,0.0002422608,0.0002699227,0.0002552964,0.0007537919],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009119645,"about_ca_system_score_gemma":0.00009017173,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002168866,"about_ca_topic_score_gemma":0.000166675,"domain_scores_codex":[0.9999139,0.000007812459,0.000008072331,0.00003834815,0.00001379974,0.00001794887],"domain_scores_gemma":[0.9999118,0.0000142465,0.00001315351,0.00001841575,0.00001476543,0.00002768785],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00133963,0.0002160265,0.03779585,0.000144698,0.00002926881,0.00288682,0.0003811403,0.0000918327,0.9052839,0.0009636957,0.000623116,0.05024409],"study_design_scores_gemma":[0.0004145165,0.005328713,0.4788396,0.000106049,0.0003204484,0.1265131,0.0008450448,0.005004078,0.3341265,0.003977214,0.04444744,0.00007727197],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9933158,0.001518761,0.002423409,0.0000460948,0.0000161455,0.00003413891,0.0002732487,0.0001420451,0.002230567],"genre_scores_gemma":[0.9948422,0.0003138036,0.001666752,0.00006694665,0.00006152645,0.00002313237,0.0005482297,0.00001959752,0.002457774],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003210021,"threshold_uncertainty_score":0.01073855,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005539558070531022,"score_gpt":0.1984059268309557,"score_spread":0.1928663687604247,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}