{"id":"W2129806278","doi":"10.4049/jimmunol.177.6.3728","title":"A New Memory CD27−IgG+ B Cell Population in Peripheral Blood Expressing VH Genes with Low Frequency of Somatic Mutation","year":2006,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":298,"is_retracted":false,"has_abstract":true,"ca_institutions":"Héma-Québec","funders":"","keywords":"Somatic hypermutation; Germinal center; Biology; Immunoglobulin D; B cell; Antibody; Naive B cell; Antigen; Population; B-1 cell; Molecular biology; Gene; Memory B cell; Somatic cell; Immunology; Genetics; T cell; Immune system; Antigen-presenting cell; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004286418,0.0002339382,0.0005655956,0.0003058756,0.0001368618,0.00001082249,0.0004227218,0.0003066926,0.0002767966],"category_scores_gemma":[0.00002885537,0.0001548105,0.0001093614,0.0002248961,0.0002976142,0.0002188257,0.00005433785,0.0005626999,0.00001928959],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000619103,"about_ca_system_score_gemma":0.0001793837,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002897136,"about_ca_topic_score_gemma":0.0003454192,"domain_scores_codex":[0.9977344,0.0006976912,0.0009713128,0.0001495974,0.00006831117,0.0003786304],"domain_scores_gemma":[0.9982116,0.0002255298,0.001106488,0.0003026579,0.0001409945,0.00001274583],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005244067,0.0003316152,0.006188688,0.00002987609,0.0002028017,0.00003732775,0.001131836,0.0006600086,0.987901,0.00009963287,0.00006352112,0.002829297],"study_design_scores_gemma":[0.00664476,0.001257087,0.03933163,0.0002038704,0.0002842051,0.002915964,0.001556827,0.0000105748,0.9455202,0.001978309,0.000057825,0.0002387621],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9713723,0.02667889,0.0007443735,0.0001839727,0.0005036196,0.0001767953,0.000002301882,0.00001687589,0.0003208601],"genre_scores_gemma":[0.9978253,0.0002245233,0.001073416,0.0000273565,0.00006467082,0.000003111576,0.00002040739,0.00002404481,0.0007371798],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0423808,"threshold_uncertainty_score":0.6312988,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005539558070531022,"score_gpt":0.1984059268309557,"score_spread":0.1928663687604247,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}